DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival
about
The CK1 Family: Contribution to Cellular Stress Response and Its Role in CarcinogenesisAkt and mTOR in B Cell Activation and DifferentiationGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)A comprehensive glossary of autophagy-related molecules and processes (2nd edition)Structural analysis and functional implications of the negative mTORC1 regulator REDD1SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myelomaSignificance of SGK1 in the regulation of neuronal functionRegulation of TOR by small GTPasesResveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTORSpatial regulation of the mTORC1 system in amino acids sensing pathwayPushing the envelope in the mTOR pathway: the second generation of inhibitorsThe mTOR signalling pathway in human cancerNext-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategyAn emerging role for TOR signaling in mammalian tissue and stem cell physiologyMammalian target of rapamycin (mTOR): conducting the cellular signaling symphonyTargeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapymTOR: from growth signal integration to cancer, diabetes and ageingmTOR signaling in growth control and diseaseCharacterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylationThe role of amino acid-induced mammalian target of rapamycin complex 1(mTORC1) signaling in insulin resistanceConserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signalingSirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular EffectsNovel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTORThe role of cullin 5-containing ubiquitin ligasesCap-Independent Translation in Hematological MalignanciesToward rapamycin analog (rapalog)-based precision cancer therapyWhat a tangled web we weave: emerging resistance mechanisms to inhibition of the phosphoinositide 3-kinase pathwayDysregulation of skeletal muscle protein metabolism by alcoholCutting through the complexities of mTOR for the treatment of strokeMany multiple myelomas: making more of the molecular mayhemPI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasmsmTOR-dependent cell survival mechanismsRegulation of mTORC1 by PI3K signalingmTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic InterventionsGSK-3 as potential target for therapeutic intervention in cancerShedding new light on neurodegenerative diseases through the mammalian target of rapamycinThe regulation of the autophagic network and its implications for human diseaseRegulation of mTORC1 by amino acidsRole of AKT/mTORC1 pathway in pancreatic β-cell proliferation
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DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
DEPTOR is an mTOR inhibitor fr ...... nd required for their survival
@ast
DEPTOR is an mTOR inhibitor fr ...... nd required for their survival
@en
DEPTOR is an mTOR inhibitor fr ...... nd required for their survival
@en-gb
DEPTOR is an mTOR inhibitor fr ...... nd required for their survival
@nl
type
label
DEPTOR is an mTOR inhibitor fr ...... nd required for their survival
@ast
DEPTOR is an mTOR inhibitor fr ...... nd required for their survival
@en
DEPTOR is an mTOR inhibitor fr ...... nd required for their survival
@en-gb
DEPTOR is an mTOR inhibitor fr ...... nd required for their survival
@nl
prefLabel
DEPTOR is an mTOR inhibitor fr ...... nd required for their survival
@ast
DEPTOR is an mTOR inhibitor fr ...... nd required for their survival
@en
DEPTOR is an mTOR inhibitor fr ...... nd required for their survival
@en-gb
DEPTOR is an mTOR inhibitor fr ...... nd required for their survival
@nl
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DEPTOR is an mTOR inhibitor fr ...... nd required for their survival
@en
P2093
Carson C Thoreen
Mathieu Laplante
Nathanael S Gray
Seong A Kang
Timothy R Peterson
W Michael Kuehl
Yasemin Sancak
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P304
P3181
P356
10.1016/J.CELL.2009.03.046
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P577
2009-05-14T00:00:00Z