The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis
about
A novel disrupter of telomere silencing 1-like (DOT1L) interaction is required for signal transducer and activator of transcription 1 (STAT1)-activated gene expressionTranscription factor Zic2 inhibits Wnt/β-catenin protein signalingWnt signaling in cartilage development and diseases: lessons from animal studiesTargets, models and challenges in osteoarthritis researchEpigenetic plasticity: a central regulator of epithelial-to-mesenchymal transition in cancerMulti-level interactions between the nuclear receptor TRα1 and the WNT effectors β-catenin/Tcf4 in the intestinal epitheliumBrg1 loss attenuates aberrant wnt-signalling and prevents wnt-dependent tumourigenesis in the murine small intestineEpigenetic regulation of the intestinal epitheliumNeuronal migration is regulated by endogenous RNAi and chromatin-binding factor ZFP-1/AF10 in Caenorhabditis elegansThe conserved PHD1-PHD2 domain of ZFP-1/AF10 is a discrete functional module essential for viability in Caenorhabditis elegansCommon variation at 10p12.31 near MLLT10 influences meningioma risk.Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritisMutations of Chromatin Structure Regulating Genes in Human Malignancies.The regulation of β-catenin activity and function in cancer: therapeutic opportunitiesDOT1L safeguards cartilage homeostasis and protects against osteoarthritis.Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling.Wnt signaling in cancerIdentification of a DNA methylation signature to predict disease-free survival in locally advanced rectal cancer.AF10 plays a key role in the survival of uncommitted hematopoietic cells.Fibroblast growth factor receptor 2c signaling is required for intestinal cell differentiation in zebrafish.Generation of an Enhancer-Trapping Vector for Insertional Mutagenesis in ZebrafishTight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics in Frzb-knockout miceAndrogen signaling is a confounding factor for β-catenin-mediated prostate tumorigenesis.Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functionsTo Wnt or not to Wnt: the bone and joint health dilemmaEpigenetics and colorectal cancer pathogenesisWnt Protein Signaling Reduces Nuclear Acetyl-CoA Levels to Suppress Gene Expression during Osteoblast Differentiation.Advances in osteoarthritis geneticsPostnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain.An investigation of the effects of the core protein telomerase reverse transcriptase on Wnt signaling in breast cancer cells.The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle.TCF/LEFs and Wnt signaling in the nucleus.Targeting genetic alterations in protein methyltransferases for personalized cancer therapeutics.Targeting the WNT Signaling Pathway in Cancer Therapeutics.Signaling and epigenetic mechanisms of intestinal stem cells and progenitors: insight into crypt homeostasis, plasticity, and niches.Patterns of Wnt signaling in the life cycle of Podocoryna carnea and its implications for medusae evolution in Hydrozoa (Cnidaria).Activation of β-catenin/TCF targets following loss of the tumor suppressor SNF5.Correction: The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis.Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms.
P2860
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P2860
The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The leukemia-associated Mllt10 ...... ial for intestinal homeostasis
@ast
The leukemia-associated Mllt10 ...... ial for intestinal homeostasis
@en
The leukemia-associated Mllt10 ...... ial for intestinal homeostasis
@nl
type
label
The leukemia-associated Mllt10 ...... ial for intestinal homeostasis
@ast
The leukemia-associated Mllt10 ...... ial for intestinal homeostasis
@en
The leukemia-associated Mllt10 ...... ial for intestinal homeostasis
@nl
prefLabel
The leukemia-associated Mllt10 ...... ial for intestinal homeostasis
@ast
The leukemia-associated Mllt10 ...... ial for intestinal homeostasis
@en
The leukemia-associated Mllt10 ...... ial for intestinal homeostasis
@nl
P2093
P2860
P50
P921
P1433
P1476
The leukemia-associated Mllt10 ...... ial for intestinal homeostasis
@en
P2093
Hans Clevers
Hans Teunissen
Harry Begthel
Jeroen Korving
Nadia Taouatas
Pantelis Hatzis
Robert G J Vries
Sylvia F Boj
Tokameh Mahmoudi
P2860
P304
P356
10.1371/JOURNAL.PBIO.1000539
P407
P577
2010-11-16T00:00:00Z