The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
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RAS Synthetic Lethal Screens Revisited: Still Seeking the Elusive Prize?RalB regulates contractility-driven cancer dissemination upon TGFβ stimulation via the RhoGEF GEF-H1Upregulation of the GEF-H1 pathway after transient cerebral ischemia.Phosphatase specificity and pathway insulation in signaling networks.Drugging the undruggable RAS: Mission possible?High-throughput workflow for identification of phosphorylated peptides by LC-MALDI-TOF/TOF-MS coupled to in situ enrichment on MALDI plates functionalized by ion landing.Mesenchymal stromal cells (MSCs) induce ex vivo proliferation and erythroid commitment of cord blood haematopoietic stem cells (CB-CD34+ cells).Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA.RANKL coordinates multiple osteoclastogenic pathways by regulating expression of ubiquitin ligase RNF146.Altered expression of cellular proliferation, apoptosis and the cell cycle-related genes in lung cancer cells with acquired resistance to EGFR tyrosine kinase inhibitors.Guanine nucleotide exchange factor -H1 promotes inflammatory cytokine production and intracellular mycobacterial elimination in macrophages.Phosphoproteomics Reveals MAPK Inhibitors Enhance MET- and EGFR-Driven AKT Signaling in KRAS-Mutant Lung Cancer.Rho GTPases: Anti- or pro-neoplastic targets?Transcriptional Regulation of miR-31 by Oncogenic KRAS Mediates Metastatic Phenotypes by Repressing RASA1Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2.A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.Autophagy suppresses cell migration by degrading GEF-H1, a RhoA GEFGuanine nucleotide exchange factor H1 can be a new biomarker of melanoma.An oncogenic KRAS transcription program activates the RHOGEF ARHGEF2 to mediate transformed phenotypes in pancreatic cancer.ARHGEF19 interacts with BRAF to activate MAPK signaling during the tumorigenesis of non-small cell lung cancer.Co-dependency between KRAS addiction and ARHGEF2 promotes an adaptive escape from MAPK pathway inhibition.Regulation of cortical stability by RhoGEF3 in mitotic Sensory Organ Precursor cells in Drosophila.Synthetic Lethal Vulnerabilities in KRAS-Mutant Cancers.New insights into RAS biology reinvigorate interest in mathematical modeling of RAS signaling.Integrative analysis reveals distinct subtypes with therapeutic implications in KRAS-mutant lung adenocarcinoma
P2860
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P2860
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
@ast
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
@en
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
@en-gb
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
@nl
type
label
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
@ast
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
@en
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
@en-gb
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
@nl
prefLabel
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
@ast
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
@en
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
@en-gb
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
@nl
P2093
P50
P921
P3181
P1433
P1476
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
@en
P2093
Benjamin G Neel
Daphna Mokady
David Meiri
Jane Cullis
Jason Moffat
Jose Larose
Josee Normand
Maria Jose Sandi
Mauricio Medrano
Nikolina Radulovich
P304
P3181
P356
10.1016/J.CCR.2014.01.025
P407
P50
P577
2014-02-10T00:00:00Z