Co-dependency between KRAS addiction and ARHGEF2 promotes an adaptive escape from MAPK pathway inhibition.

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Co-dependency between KRAS addiction and ARHGEF2 promotes an adaptive escape from MAPK pathway inhibition.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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Co-dependency between KRAS add ...... from MAPK pathway inhibition.

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Co-dependency between KRAS add ...... from MAPK pathway inhibition.

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Co-dependency between KRAS add ...... from MAPK pathway inhibition.

@en

Co-dependency between KRAS add ...... from MAPK pathway inhibition.

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Co-dependency between KRAS add ...... from MAPK pathway inhibition.

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Co-dependency between KRAS add ...... from MAPK pathway inhibition.

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P1476

Co-dependency between KRAS add ...... e from MAPK pathway inhibition

@en

P2093

Maria-Jose Sandi

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P2860

Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases

Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton

The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

Molecular targets for the treatment of pancreatic cancer: Clinical and experimental studies

Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?

A randomised, double-blind, placebo-controlled trial of trametinib, an oral MEK inhibitor, in combination with gemcitabine for patients with untreated metastatic adenocarcinoma of the pancreas.

Mutations of the BRAF gene in human cancer

Rho GTPases in cell biology

The consensus coding sequences of human breast and colorectal cancers

P304

441-448

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P31

scholarly article

P356

10.1080/21541248.2017.1337545

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P433

http://www.w3.org/2001/XMLSchema#string

P478

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P50

Robert Rottapel

Oliver A Kent

Maria-Jose Sandi

P577

2017-07-11T00:00:00Z

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P698

28656876

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P932

6748365

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