Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes - Wikidata - wikimedia - TriplyDB

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

http://www.wikidata.org/entity/Q24534154

about

In vitro nuclear interactome of the HIV-1 Tat protein Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities Pf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complex Identification and characterization of SAP25, a novel component of the mSin3 corepressor complex.COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein Histone deacetylases (HDACs): characterization of the classical HDAC family A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: inhibition of the myogenic program Neural restrictive silencer factor recruits mSin3 and histone deacetylase complex to repress neuron-specific target genes Expression of histone deacetylase 8, a class I histone deacetylase, is restricted to cells showing smooth muscle differentiation in normal human tissues mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad Congenital pancytopenia and absence of B lymphocytes in a neonate with a mutation in the Ikaros gene Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif Colocalization and heteromerization between the two human oncogene POZ/zinc finger proteins, LAZ3 (BCL6) and PLZF Ikaros gene expression and leukemia Ikaros-CtIP interactions do not require C-terminal binding protein and participate in a deacetylase-independent mode of repression Unconventional potentiation of gene expression by Ikaros Vasoactive intestinal peptide receptor-1 (VPAC-1) is a novel gene target of the hemolymphopoietic transcription factor Ikaros A molecular dissection of the repression circuitry of Ikaros A conserved 12-amino acid motif in Sall1 recruits the nucleosome remodeling and deacetylase corepressor complex HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator Trichostatin A inhibits beta-casein expression in mammary epithelial cells Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos Multiple hematopoietic defects and delayed globin switching in Ikaros null mice A positive regulatory role for the mSin3A-HDAC complex in pluripotency through Nanog and Sox2 mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival Ikaros integrates endocrine and immune system development Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency The Ikaros family protein Eos associates with C-terminal-binding protein corepressors Ikaros SUMOylation: switching out of repression Myt1 family recruits histone deacetylase to regulate neural transcription.Identification of two Ikaros-like transcription factors in lamprey.Expression of a unique helios isoform in human leukemia cells.Probing lysine acetylation in proteins: strategies, limitations, and pitfalls of in vitro acetyltransferase assays.DNA replication progresses on the periphery of nuclear aggregates formed by the BCL6 transcription factor Sequence analysis of mouse vomeronasal receptor gene clusters reveals common promoter motifs and a history of recent expansion.Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo Silencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1.

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P2860

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

http://www.wikidata.org/entity/Q24534154

description

1999 nî lūn-bûn

@nan

1999 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի հունիսին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

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1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

@ast

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

@en

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

@nl

type

label

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

@ast

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

@en

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

@nl

prefLabel

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

@ast

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

@en

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

@nl

P1433

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P1433

The EMBO Journal

P1476

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

@en

P2093

A Renold

http://www.w3.org/2001/XMLSchema#string

J Kim

http://www.w3.org/2001/XMLSchema#string

J Koipally

http://www.w3.org/2001/XMLSchema#string

K Georgopoulos

http://www.w3.org/2001/XMLSchema#string

P2860

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex

CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex

Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation

Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia

Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development

A histone deacetylase corepressor complex regulates the Notch signal transduction pathway

Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin

The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene

Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

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3090-100

http://www.w3.org/2001/XMLSchema#string

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scholarly article

P3181

613425

http://www.w3.org/2001/XMLSchema#string

P356

10.1093/EMBOJ/18.11.3090

http://www.w3.org/2001/XMLSchema#string

P407

P433

11

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P478

18

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P577

1999-06-01T00:00:00Z

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P5875

12940760

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P698

10357820

http://www.w3.org/2001/XMLSchema#string

P932

1171390

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