The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis
about
Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organismsTACC1-chTOG-Aurora A protein complex in breast cancerCarcinogenesis and translational controls: TACC1 is down-regulated in human cancers and associates with mRNA regulatorsCep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cellsRHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stabilityAberrations of TACC1 and TACC3 are associated with ovarian cancerTIPsy tour guides: how microtubule plus-end tracking proteins (+TIPs) facilitate axon guidanceTACC3 Is Important for Correct Progression of Meiosis in Bovine OocytesAurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle AssemblyExploring the developmental mechanisms underlying Wolf-Hirschhorn Syndrome: Evidence for defects in neural crest cell migrationSpecific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension.A classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3MCAK-independent functions of ch-Tog/XMAP215 in microtubule plus-end dynamics.Loggerhead sea turtle embryos (Caretta caretta) regulate expression of stress response and developmental genes when exposed to a biologically realistic heat stress.TACC2 is an androgen-responsive cell cycle regulator promoting androgen-mediated and castration-resistant growth of prostate cancerIdentification of stem cell transcriptional programs normally expressed in embryonic and neural stem cells in alloreactive CD8+ T cells mediating graft-versus-host diseaseA small molecule accelerates neuronal differentiation in the adult rat.Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes.Chemical biology in stem cell research.Transforming acidic coiled-coil protein-3 (Tacc3) acts as a negative regulator of Notch signaling through binding to CDC10/Ankyrin repeatsThe transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival.Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway.Centrosomal TACCtics.TACC3 is essential for EGF-mediated EMT in cervical cancerCoactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-BThe centrosomal, putative tumor suppressor protein TACC2 is dispensable for normal development, and deficiency does not lead to cancerMoMuLV-ts-1: A Unique Mouse Model of Retrovirus-Induced Lymphoma Transmitted by Breast Milk.High expression of TACC3 in esophageal squamous cell carcinoma correlates with poor prognosis.Transforming acidic coiled-coil 3 and Aurora-A interact in human thyrocytes and their expression is deregulated in thyroid cancer tissues.TACC3 promotes stemness and is a potential therapeutic target in hepatocellular carcinoma.Mitosis-specific anchoring of gamma tubulin complexes by pericentrin controls spindle organization and mitotic entryTACC3 promotes colorectal cancer tumourigenesis and correlates with poor prognosisThe centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program.Changes in protein expression of pacific oyster Crassostrea gigas exposed in situ to urban sewage.Transforming acidic coiled-coil protein 3 (TACC3) controls friend of GATA-1 (FOG-1) subcellular localization and regulates the association between GATA-1 and FOG-1 during hematopoiesis.The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.Interaction of TACC proteins with the FHL family: implications for ERK signaling.TACC3 depletion sensitizes to paclitaxel-induced cell death and overrides p21WAF-mediated cell cycle arrest.Report of a patient and further clinical and molecular characterization of interstitial 4p16.3 microduplication.
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P2860
The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis
description
2002 nî lūn-bûn
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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The centrosomal protein TACC3 ...... s with p53-regulated apoptosis
@ast
The centrosomal protein TACC3 ...... s with p53-regulated apoptosis
@en
The centrosomal protein TACC3 ...... s with p53-regulated apoptosis
@en-gb
The centrosomal protein TACC3 ...... s with p53-regulated apoptosis
@nl
type
label
The centrosomal protein TACC3 ...... s with p53-regulated apoptosis
@ast
The centrosomal protein TACC3 ...... s with p53-regulated apoptosis
@en
The centrosomal protein TACC3 ...... s with p53-regulated apoptosis
@en-gb
The centrosomal protein TACC3 ...... s with p53-regulated apoptosis
@nl
prefLabel
The centrosomal protein TACC3 ...... s with p53-regulated apoptosis
@ast
The centrosomal protein TACC3 ...... s with p53-regulated apoptosis
@en
The centrosomal protein TACC3 ...... s with p53-regulated apoptosis
@en-gb
The centrosomal protein TACC3 ...... s with p53-regulated apoptosis
@nl
P2093
P2860
P3181
P356
P1433
P1476
The centrosomal protein TACC3 ...... s with p53-regulated apoptosis
@en
P2093
Angelika Hoffmeyer
Catriona McKay
Christopher D Duntsch
Hideaki Nakajima
James N Ihle
Jerold Rehg
Linda Snyder
Roland P Piekorz
Veronika Sexl
P2860
P304
P3181
P356
10.1093/EMBOJ/21.4.653
P407
P577
2002-02-01T00:00:00Z