Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain - Wikidata - wikimedia - TriplyDB

Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain

Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain

http://www.wikidata.org/entity/Q24536014

about

ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2 Autoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandem Signal-dependent membrane targeting by pleckstrin homology (PH) domains The amyloid-beta precursor protein: integrating structure with biological function Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain Structure of the PTB domain of tensin1 and a model for its recruitment to fibrillar adhesions Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's disease A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission Amyloid-beta Alzheimer targets - protein processing, lipid rafts, and amyloid-beta pores Alzheimer's disease--a panorama glimpse Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1 Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex.Crystal structures of the Dab homology domains of mouse disabled 1 and 2 Crystal structure of the human Fe65-PTB1 domain Structure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein reveals a novel peptide binding mode Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2 Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing Solution structure and peptide binding of the PTB domain from the AIDA1 postsynaptic signaling scaffolding protein Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity Modulation of amyloid precursor protein metabolism by X11alpha /Mint-1. A deletion analysis of protein-protein interaction domains.The neuronal adaptor protein X11alpha interacts with the copper chaperone for SOD1 and regulates SOD1 activity Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease Interaction domains: from simple binding events to complex cellular behavior Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin The phosphotyrosine binding-like domain of talin activates integrins Synergistic effects of Munc18a and X11 proteins on amyloid precursor protein metabolism The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNX Interaction of Mint2 with TrkA is involved in regulation of nerve growth factor-induced neurite outgrowth Structural basis for the disruption of the cerebral cavernous malformations 2 (CCM2) interaction with Krev interaction trapped 1 (KRIT1) by disease-associated mutations Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.Screening for PTB domain binding partners and ligand specificity using proteome-derived NPXY peptide arrays.Structural conservation in band 4.1, ezrin, radixin, moesin (FERM) domains as a guide to identify inhibitors of the proline-rich tyrosine kinase 2.Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain.The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids PTB or not PTB -- that is the question.A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function.Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis.

P2860

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P2860

Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain

http://www.wikidata.org/entity/Q24536014

description

1997 nî lūn-bûn

@nan

1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

1997年の論文

@ja

1997年論文

@yue

1997年論文

@zh-hant

1997年論文

@zh-hk

1997年論文

@zh-mo

1997年論文

@zh-tw

1997年论文

@wuu

name

Sequence-specific recognition ...... protein by the X11 PTB domain

@ast

Sequence-specific recognition ...... protein by the X11 PTB domain

@en

Sequence-specific recognition ...... protein by the X11 PTB domain

@nl

type

label

Sequence-specific recognition ...... protein by the X11 PTB domain

@ast

Sequence-specific recognition ...... protein by the X11 PTB domain

@en

Sequence-specific recognition ...... protein by the X11 PTB domain

@nl

prefLabel

Sequence-specific recognition ...... protein by the X11 PTB domain

@ast

Sequence-specific recognition ...... protein by the X11 PTB domain

@en

Sequence-specific recognition ...... protein by the X11 PTB domain

@nl

P1433

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P2860

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P1433

The EMBO Journal

P1476

Sequence-specific recognition ...... protein by the X11 PTB domain

@en

P2093

Kuriyan J

http://www.w3.org/2001/XMLSchema#string

Mandiyan V

http://www.w3.org/2001/XMLSchema#string

Margolis B

http://www.w3.org/2001/XMLSchema#string

Schlessinger J

http://www.w3.org/2001/XMLSchema#string

Zhang Z

http://www.w3.org/2001/XMLSchema#string

P2860

Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal

The phosphotyrosine interaction domain of Shc binds an LXNPXY motif on the epidermal growth factor receptor

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

SH2 domains exhibit high-affinity binding to tyrosine-phosphorylated peptides yet also exhibit rapid dissociation and exchange

Gene in the region of the Friedreich ataxia locus encodes a putative transmembrane protein expressed in the nervous system

A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase

Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

P304

6141-6150

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scholarly article

P3181

4073356

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P356

10.1093/EMBOJ/16.20.6141

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P407

P433

20

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P478

16

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P50

P577

1997-10-01T00:00:00Z

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P5875

13904585

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P698

9321393

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P921

Alzheimer's disease

P932

1326298

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