Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms
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DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositidesMolecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinaseAlternative modes of binding of proteins with tandem SH2 domainsStructural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteinsStructural insight into the binding diversity between the Tyr-phosphorylated human ephrinBs and Nck2 SH2 domainCsk homologous kinase (CHK) and ErbB-2 interactions are directly coupled with CHK negative growth regulatory function in breast cancerRegulation of FynT function by dual domain docking on PAG/CbpPleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptorMeasurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisalStructural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motifRequirements for interleukin-4-induced gene expression and functional characterization of Stat6Structural determinants of the interaction between the erbB2 receptor and the Src homology 2 domain of Grb7Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptorMutational analysis of the STAT6 SH2 domainSyntrophin binds to an alternatively spliced exon of dystrophinIdentification of Nck family genes, chromosomal localization, expression, and signaling specificityIdentification of amino acid residues critical for the Src-homology 2 domain-dependent docking of Stat2 to the interferon alpha receptorDifferential functions of the two Src homology 2 domains in protein tyrosine phosphatase SH-PTP1A novel phosphotyrosine motif with a critical amino acid at position -2 for the SH2 domain-mediated activation of the tyrosine phosphatase SHP-1The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding siteGrb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptorsPhosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 proteinBcr-Abl oncoproteins bind directly to activators of the Ras signalling pathwayStructure of a specific peptide complex of the carboxy-terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3-kinaseInteraction of phosphorylated FcepsilonRIgamma immunoglobulin receptor tyrosine activation motif-based peptides with dual and single SH2 domains of p72syk. Assessment of binding parameters and real time binding kineticsThe human GRB2 and Drosophila Drk genes can functionally replace the Caenorhabditis elegans cell signaling gene sem-5.Kinase activation through dimerization by human SH2-BSHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain.Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cellsSequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domainVav family proteins couple to diverse cell surface receptorsA novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptorsA mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brainCharacterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5)The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5pMapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kGenetic analysis of a phosphatidylinositol 3-kinase SH2 domain reveals determinants of specificityThe T-cell antigen CD5 acts as a receptor and substrate for the protein-tyrosine kinase p56lckAutophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src
P2860
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P2860
Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms
description
1993 nî lūn-bûn
@nan
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Binding of a high affinity pho ...... mplexed and peptide-free forms
@ast
Binding of a high affinity pho ...... mplexed and peptide-free forms
@en
Binding of a high affinity pho ...... mplexed and peptide-free forms
@nl
type
label
Binding of a high affinity pho ...... mplexed and peptide-free forms
@ast
Binding of a high affinity pho ...... mplexed and peptide-free forms
@en
Binding of a high affinity pho ...... mplexed and peptide-free forms
@nl
prefLabel
Binding of a high affinity pho ...... mplexed and peptide-free forms
@ast
Binding of a high affinity pho ...... mplexed and peptide-free forms
@en
Binding of a high affinity pho ...... mplexed and peptide-free forms
@nl
P2093
P1433
P1476
Binding of a high affinity pho ...... mplexed and peptide-free forms
@en
P2093
P304
P356
10.1016/0092-8674(93)90405-F
P407
P577
1993-03-12T00:00:00Z