U11 snRNA interacts in vivo with the 5' splice site of U12-dependent (AU-AC) pre-mRNA introns
about
The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosomeRecycling of the U12-type spliceosome requires p110, a component of the U6atac snRNPA novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.Base pairing with U6atac snRNA is required for 5' splice site activation of U12-dependent introns in vivo.Conservation of functional features of U6atac and U12 snRNAs between vertebrates and higher plantsThe human Prp8 protein is a component of both U2- and U12-dependent spliceosomesDomains of human U4atac snRNA required for U12-dependent splicing in vivoTargeted 'knockdown' of spliceosome function in mammalian cellsAn intronic enhancer regulates splicing of the twintron of Drosophila melanogaster prospero pre-mRNA by two different spliceosomesA SMN missense mutation complements SMN2 restoring snRNPs and rescuing SMA miceSite-specific crosslinking of mammalian U11 and u6atac to the 5' splice site of an AT-AC intronIdentification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in DrosophilaThe significant other: splicing by the minor spliceosomeA mutation in a rare type of intron in a sodium-channel gene results in aberrant splicing and causes myotonia.Evolutionary dynamics of U12-type spliceosomal introns.Efficient polyadenylation of Rous sarcoma virus RNA requires the negative regulator of splicing elementAT-AC pre-mRNA splicing mechanisms and conservation of minor introns in voltage-gated ion channel genes.U1 small nuclear ribonucleoprotein and splicing inhibition by the rous sarcoma virus negative regulator of splicing element.Interaction between the negative regulator of splicing element and a 3' splice site: requirement for U1 small nuclear ribonucleoprotein and the 3' splice site branch point/pyrimidine tract.Gene expression profiling of U12-type spliceosome mutant Drosophila reveals widespread changes in metabolic pathwaysThe U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11-59K proteinRole of the 3' splice site in U12-dependent intron splicingU4 small nuclear RNA can function in both the major and minor spliceosomes.The role of overlapping U1 and U11 5' splice site sequences in a negative regulator of splicingA limited number of pseudouridine residues in the human atac spliceosomal UsnRNAs as compared to human major spliceosomal UsnRNAsThe intramolecular stem-loop structure of U6 snRNA can functionally replace the U6atac snRNA stem-loopAlternative splicing of U12-dependent introns in vivo responds to purine-rich enhancersSolution structure of the pseudo-5' splice site of a retroviral splicing suppressor.A mutational analysis of U12-dependent splice site dinucleotides.The abundance of the spliceosomal snRNPs is not limiting the splicing of U12-type introns.Initial recognition of U12-dependent introns requires both U11/5' splice-site and U12/branchpoint interactionsFunctionally important structural elements of U12 snRNAMutational analysis of the U12-dependent branch site consensus sequence.The Arabidopsis homolog of human minor spliceosomal protein U11-48K plays a crucial role in U12 intron splicing and plant developmentU6atac snRNA stem-loop interacts with U12 p65 RNA binding protein and is functionally interchangeable with the U12 apical stem-loop III.The conserved 3' end domain of U6atac snRNA can direct U6 snRNA to the minor spliceosome.The U11-48K protein contacts the 5' splice site of U12-type introns and the U11-59K protein.An RNA splicing enhancer-like sequence is a component of a splicing inhibitor element from Rous sarcoma virus.Analysis of canonical and non-canonical splice sites in mammalian genomesHuman U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions.
P2860
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P2860
U11 snRNA interacts in vivo with the 5' splice site of U12-dependent (AU-AC) pre-mRNA introns
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
U11 snRNA interacts in vivo wi ...... ndent (AU-AC) pre-mRNA introns
@ast
U11 snRNA interacts in vivo wi ...... ndent (AU-AC) pre-mRNA introns
@en
U11 snRNA interacts in vivo wi ...... ndent (AU-AC) pre-mRNA introns
@nl
type
label
U11 snRNA interacts in vivo wi ...... ndent (AU-AC) pre-mRNA introns
@ast
U11 snRNA interacts in vivo wi ...... ndent (AU-AC) pre-mRNA introns
@en
U11 snRNA interacts in vivo wi ...... ndent (AU-AC) pre-mRNA introns
@nl
prefLabel
U11 snRNA interacts in vivo wi ...... ndent (AU-AC) pre-mRNA introns
@ast
U11 snRNA interacts in vivo wi ...... ndent (AU-AC) pre-mRNA introns
@en
U11 snRNA interacts in vivo wi ...... ndent (AU-AC) pre-mRNA introns
@nl
P3181
P1433
P1476
U11 snRNA interacts in vivo wi ...... ndent (AU-AC) pre-mRNA introns
@en
P2093
Kolossova I
Padgett RA
P304
P3181
P407
P577
1997-03-01T00:00:00Z