The molecular characterization of PRP6 and PRP9 yeast genes reveals a new cysteine/histidine motif common to several splicing factors
about
A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicingSplicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivoCharacterization and cloning of the human splicing factor 9G8: a novel 35 kDa factor of the serine/arginine protein familyHomodimerization of the human U1 snRNP-specific protein CA novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleusDomains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formationSpecific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reactionStructure and assembly of the SF3a splicing factor complex of U2 snRNPYeast pre-mRNA splicing requires a pair of U1 snRNP-associated tetratricopeptide repeat proteins.The yeast PRP6 gene encodes a U4/U6 small nuclear ribonucleoprotein particle (snRNP) protein, and the PRP9 gene encodes a protein required for U2 snRNP bindingThe DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome.Yeast ortholog of the Drosophila crooked neck protein promotes spliceosome assembly through stable U4/U6.U5 snRNP addition.The biochemical defects of prp4-1 and prp6-1 yeast splicing mutants reveal that the PRP6 protein is required for the accumulation of the [U4/U6.U5] tri-snRNP.STP1, a gene involved in pre-tRNA processing, encodes a nuclear protein containing zinc finger motifs.p62cdc23 of Saccharomyces cerevisiae: a nuclear tetratricopeptide repeat protein with two mutable domains.Identification and characterization of a yeast homolog of U1 snRNP-specific protein CMultiple developmental requirements of noisette, the Drosophila homolog of the U2 snRNP-associated polypeptide SP3a60.Structural variety of arginine-rich RNA-binding peptides.The hangover gene defines a stress pathway required for ethanol tolerance developmentAAR2, a gene for splicing pre-mRNA of the MATa1 cistron in cell type control of Saccharomyces cerevisiae.Proteins associated with SF3a60 in T. brucei.The tgl gene: social motility and stimulation in Myxococcus xanthus.Evidence that the 60-kDa protein of 17S U2 small nuclear ribonucleoprotein is immunologically and functionally related to the yeast PRP9 splicing factor and is required for the efficient formation of prespliceosomes.Human adenovirus encodes two proteins which have opposite effects on accumulation of alternatively spliced mRNAs.A yeast splicing factor is localized in discrete subnuclear domains.Proteins involved in mitosis, RNA synthesis and premRNA splicing share a common repeating motif.A novel gene, spp91-1, suppresses the splicing defect and the pre-mRNA nuclear export in the prp9-1 mutant.Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing.The prp1+ gene required for pre-mRNA splicing in Schizosaccharomyces pombe encodes a protein that contains TPR motifs and is similar to Prp6p of budding yeast.
P2860
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P2860
The molecular characterization of PRP6 and PRP9 yeast genes reveals a new cysteine/histidine motif common to several splicing factors
description
1990 nî lūn-bûn
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1990 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
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1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
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1990年论文
@wuu
name
The molecular characterization ...... on to several splicing factors
@ast
The molecular characterization ...... on to several splicing factors
@en
The molecular characterization ...... on to several splicing factors
@nl
type
label
The molecular characterization ...... on to several splicing factors
@ast
The molecular characterization ...... on to several splicing factors
@en
The molecular characterization ...... on to several splicing factors
@nl
prefLabel
The molecular characterization ...... on to several splicing factors
@ast
The molecular characterization ...... on to several splicing factors
@en
The molecular characterization ...... on to several splicing factors
@nl
P2860
P1433
P1476
The molecular characterization ...... on to several splicing factors
@en
P2093
P2860
P304
P407
P577
1990-09-01T00:00:00Z