NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression - Wikidata - wikimedia - TriplyDB

NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression

NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression

http://www.wikidata.org/entity/Q24556668

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Nuclear factor of activated T cells - a transcription factor family as critical regulator in lung and colon cancer T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation Enforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathology Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt The transcription factor NFATc2 controls IL-6-dependent T cell activation in experimental colitis Cytokines as Adjuvants for Vaccine and Cellular Therapies for Cancer.IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?Autism and nutrition: the role of the gut-brain axis.The IL-21 receptor augments Th2 effector function and alternative macrophage activation Early Th1 cell differentiation is marked by a Tfh cell-like transition.Nuclear factor of activated T cells 1 (NFAT1)-induced permissive chromatin modification facilitates nuclear factor-κB (NF-κB)-mediated interleukin-9 (IL-9) transactivation.IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter.Interleukin 21: a cytokine/cytokine receptor system that has come of age IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor.IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype.CD8+ Th17 mediate costimulation blockade-resistant allograft rejection in T-bet-deficient mice NFAT2 Regulates Generation of Innate-Like CD8+ T Lymphocytes and CD8+ T Lymphocytes Responses.Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus CD4 T Follicular Helper Cells and HIV Infection: Friends or Enemies?Targeting interleukin-21 in inflammatory diseases.T-bet employs diverse regulatory mechanisms to repress transcription.IL-21 as a therapeutic target in inflammatory disorders.Development and characterization of IL-21-producing CD4+ T cells CREM Alpha Enhances IL-21 Production in T Cells In Vivo and In Vitro.Calcium-dependent activation of interleukin-21 gene expression in T cells.T-bet's ability to regulate individual target genes requires the conserved T-box domain to recruit histone methyltransferase activity and a separate family member-specific transactivation domain.Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection.T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype.The common gamma chain cytokine interleukin-21 is expressed by activated lymphocytes from two macropod marsupials, Macropus eugenii and Onychogalea fraenata.Role of IL-21 in inflammatory bowel disease.NFATc1 deficiency in T cells protects mice from experimental autoimmune encephalomyelitis.Interleukin-21 suppresses the differentiation and functions of T helper 2 cells.MyD88 Signaling in T Cells Is Critical for Effector CD4 T Cell Differentiation following a Transitional T Follicular Helper Cell Stage.The PTPN22 1858T allele but not variants in the proximal promoter region of IL-21 gene is associated with the susceptibility to type 1 diabetes and the presence of autoantibodies in a Brazilian cohort

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NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression

http://www.wikidata.org/entity/Q24556668

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2005 nî lūn-bûn

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2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2005 թվականի փետրվարին հրատարակված գիտական հոդված

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2005年の論文

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2005年学术文章

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NFATc2 and T-bet contribute to ...... regulation of IL-21 expression

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PNAS.0409512102

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Proceedings of the National Academy of Sciences of the United States of America

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NFATc2 and T-bet contribute to ...... regulation of IL-21 expression

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Amy S Weinmann

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Andrea L Wurster

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Devangi S Mehta

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Michael J Grusby

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P2860

Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

A novel transcription factor, T-bet, directs Th1 lineage commitment

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

Use of chromatin immunoprecipitation to clone novel E2F target promoters

Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells

The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines

MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

MODBASE, a database of annotated comparative protein structure models, and associated resources.

rVISTA 2.0: evolutionary analysis of transcription factor binding sites.

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2016-21

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3103132

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10.1073/PNAS.0409512102

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6

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102

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8048422

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15684054

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548571

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