DDB1 maintains genome integrity through regulation of Cdt1 - Wikidata - wikimedia - TriplyDB

DDB1 maintains genome integrity through regulation of Cdt1

DDB1 maintains genome integrity through regulation of Cdt1

http://www.wikidata.org/entity/Q33255742

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RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells.Prevention of DNA re-replication in eukaryotic cells Replication licensing and cancer--a fatal entanglement?Mechanisms to control rereplication and implications for cancer.DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle Re-replication of a centromere induces chromosomal instability and aneuploidy 5-AED enhances survival of irradiated mice in a G-CSF-dependent manner, stimulates innate immune cell function, reduces radiation-induced DNA damage and induces genes that modulate cell cycle progression and apoptosis CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis CRL4Cdt2: master coordinator of cell cycle progression and genome stability HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase.Checkpoint effects and telomere amplification during DNA re-replication in fission yeast.The basic cleft of RPA70N binds multiple checkpoint proteins, including RAD9, to regulate ATR signaling.Damaged DNA-binding protein 1 (DDB1) interacts with Cdh1 and modulates the function of APC/CCdh1.Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R.Crossover localisation is regulated by the neddylation posttranslational regulatory pathway.CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase.Hepatocyte-specific deletion of DDB1 induces liver regeneration and tumorigenesis Single-stranded annealing induced by re-initiation of replication origins provides a novel and efficient mechanism for generating copy number expansion via non-allelic homologous recombination.Non-canonical CRL4A/4B(CDT2) interacts with RAD18 to modulate post replication repair and cell survival.Regulation of DNA damage response pathways by the cullin-RING ubiquitin ligases Cdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells.Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation.DDB1 is essential for genomic stability in developing epidermis.Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair response DDB2, DDB1A and DET1 exhibit complex interactions during Arabidopsis development.Regulation of cell cycle progression by forkhead transcription factor FOXO3 through its binding partner DNA replication factor Cdt1.Epidermal growth factor receptor protects proliferating cell nuclear antigen from cullin 4A protein-mediated proteolysis."The Octet": Eight Protein Kinases that Control Mammalian DNA Replication.Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1 Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control Epstein-Barr virus latent membrane protein 1 represses DNA repair through the PI3K/Akt/FOXO3a pathway in human epithelial cells.Cdt1 and Cdc6 are destabilized by rereplication-induced DNA damage.Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.Activation of a human chromosomal replication origin by protein tethering.Repression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts.Cyclin-dependent kinase 2 dependent phosphorylation of ATRIP regulates the G2-M checkpoint response to DNA damage.DNA replication licensing control and rereplication prevention.Ub-family modifications at the replication fork: Regulating PCNA-interacting components.CRL Ubiquitin Ligases and DNA Damage Response.

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DDB1 maintains genome integrity through regulation of Cdt1

http://www.wikidata.org/entity/Q33255742

description

2006 nî lūn-bûn

@nan

2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի օգոստոսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

@zh-hk

2006年論文

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2006年論文

@zh-tw

2006年论文

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name

DDB1 maintains genome integrity through regulation of Cdt1

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DDB1 maintains genome integrity through regulation of Cdt1

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DDB1 maintains genome integrity through regulation of Cdt1

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DDB1 maintains genome integrity through regulation of Cdt1

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DDB1 maintains genome integrity through regulation of Cdt1

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DDB1 maintains genome integrity through regulation of Cdt1

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P1433

Molecular and Cellular Biology

P1476

DDB1 maintains genome integrity through regulation of Cdt1

@en

P2093

Ashwini Yenamandra

http://www.w3.org/2001/XMLSchema#string

Courtney A Lovejoy

http://www.w3.org/2001/XMLSchema#string

David Cortez

http://www.w3.org/2001/XMLSchema#string

Kimberli Lock

http://www.w3.org/2001/XMLSchema#string

P2860

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

A role for ATR in the DNA damage-induced phosphorylation of p53

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair

Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

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7977-7990

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scholarly article

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10.1128/MCB.00819-06

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21

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26

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2006-08-28T00:00:00Z

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16940174

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1636754

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