Functional and biochemical dissection of the structure-specific nuclease ARTEMIS - Wikidata - wikimedia - TriplyDB

Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

http://www.wikidata.org/entity/Q24564574

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The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases A CPSF-73 homologue is required for cell cycle progression but not cell growth and interacts with a protein having features of CPSF-100 DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2 The hSNM1 protein is a DNA 5'-exonuclease Extent to which hairpin opening by the Artemis:DNA-PKcs complex can contribute to junctional diversity in V(D)J recombination The Chemical Biology of Human Metallo-β-Lactamase Fold Proteins Structural and functional characterization ofSalmonella entericaserovar Typhimurium YcbL: An unusual Type II glyoxalase Phosphorylation of Artemis following irradiation-induced DNA damage.The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis.DNA-PKcs dependence of Artemis endonucleolytic activity, differences between hairpins and 5' or 3' overhangs.Non-homologous end-joining, a sticky affair Apollo contributes to G overhang maintenance and protects leading-end telomeres SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegans Clinical and Molecular Heterogeneity of RTEL1 Deficiency Nonhomologous end joining: a good solution for bad ends The multifunctional SNM1 gene family: not just nucleases The telomeric protein SNM1B/Apollo is required for normal cell proliferation and embryonic development.Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair.The importance of safeguarding genome integrity in germination and seed longevity.Functional analysis of the purified anandamide-generating phospholipase D as a member of the metallo-beta-lactamase family.DNA double-strand break repair in Caenorhabditis elegans Nucleases of the metallo-beta-lactamase family and their role in DNA and RNA metabolism.DNA ligase IV and artemis act cooperatively to suppress homologous recombination in human cells: implications for DNA double-strand break repair.Novel spontaneous deletion of artemis exons 10 and 11 in mice leads to T- and B-cell deficiency Restoration of G1 chemo/radioresistance and double-strand-break repair proficiency by wild-type but not endonuclease-deficient Artemis.Functional analysis of naturally occurring DCLRE1C mutations and correlation with the clinical phenotype of ARTEMIS deficiency Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation.The role of DNA-PKcs and artemis in opening viral DNA hairpin termini in various tissues in mice.Unifying the DNA end-processing roles of the artemis nuclease: Ku-dependent artemis resection at blunt DNA ends.DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency.V(D)J and immunoglobulin class switch recombinations: a paradigm to study the regulation of DNA end-joining.Artemis regulates cell cycle recovery from the S phase checkpoint by promoting degradation of cyclin E.Evidence that the DNA endonuclease ARTEMIS also has intrinsic 5'-exonuclease activity.Coordination of DNA-PK activation and nuclease processing of DNA termini in NHEJ.Molecular nature of radiation injury and DNA repair disorders associated with radiosensitivity.

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Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

http://www.wikidata.org/entity/Q24564574

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2004 nî lūn-bûn

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2004 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2004 թվականի մայիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

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Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

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Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

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type

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Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

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Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

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Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

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Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

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Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

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Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

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SJ.EMBOJ.7600206

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The EMBO Journal

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Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

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P2093

Doris Niewolik

http://www.w3.org/2001/XMLSchema#string

Klaus Schwarz

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Michael R Lieber

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Ulrich Pannicke

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Yunmei Ma

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P2860

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family.

Nonhomologous end joining and V(D)J recombination require an additional factor

The metallo-beta-lactamase/beta-CASP domain of Artemis constitutes the catalytic core for V(D)J recombination

The beta-lactamase motif in Snm1 is required for repair of DNA double-strand breaks caused by interstrand crosslinks in S. cerevisiae.

The RAG proteins and V(D)J recombination: complexes, ends, and transposition

Mechanistic constraints on diversity in human V(D)J recombination

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

Defective DNA repair and increased genomic instability in Artemis-deficient murine cells

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1987-97

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10.1038/SJ.EMBOJ.7600206

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9

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23

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Karl-Peter Hopfner

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2004-05-05T00:00:00Z

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8629334

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15071507

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404326

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