The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis.
about
Phosphorylation: the molecular switch of double-strand break repairThe mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayExtent to which hairpin opening by the Artemis:DNA-PKcs complex can contribute to junctional diversity in V(D)J recombinationTerminal DNA structure and ATP influence binding parameters of the DNA-dependent protein kinase at an early step prior to DNA synapsis.DNA-PK: a dynamic enzyme in a versatile DSB repair pathwayDNA-PK autophosphorylation facilitates Artemis endonuclease activityDNA-PKcs dependence of Artemis endonucleolytic activity, differences between hairpins and 5' or 3' overhangs.XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gapsArtemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcsThe DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosisNon-homologous end-joining, a sticky affairFlexibility in the order of action and in the enzymology of the nuclease, polymerases, and ligase of vertebrate non-homologous DNA end joining: relevance to cancer, aging, and the immune systemRole of non-homologous end joining in V(D)J recombinationMechanisms for Structural Variation in the Human GenomeDNA double strand break repair enzymes function at multiple steps in retroviral infection.Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex.Replication protein A: directing traffic at the intersection of replication and repair.The multifunctional SNM1 gene family: not just nucleasesEssential factors for incompatible DNA end joining at chromosomal DNA double strand breaks in vivo.BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair.Mechanisms of double-strand break repair in somatic mammalian cells.Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.End-processing during non-homologous end-joining: a role for exonuclease 1A structural model for regulation of NHEJ by DNA-PKcs autophosphorylationNucleases of the metallo-beta-lactamase family and their role in DNA and RNA metabolism.Involvement of DNA-dependent protein kinase in normal cell cycle progression through mitosis.Differential role of DNA-PKcs phosphorylations and kinase activity in radiosensitivity and chromosomal instability.Nonhomologous DNA end joining (NHEJ) and chromosomal translocations in humansCongenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair.Scanning fluorescence correlation spectroscopy techniques to quantify the kinetics of DNA double strand break repair proteins after γ-irradiation and bleomycin treatment.Choosing the right path: does DNA-PK help make the decision?Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3' exonuclease and can participate in DNA end joining in a biochemical system.Smarcal1 promotes double-strand-break repair by nonhomologous end-joining.DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys?Cryo-EM structure of the DNA-dependent protein kinase catalytic subunit at subnanometer resolution reveals alpha helices and insight into DNA binding.The N-terminal region of the DNA-dependent protein kinase catalytic subunit is required for its DNA double-stranded break-mediated activation.Isolation and characterization of a novel H1.2 complex that acts as a repressor of p53-mediated transcription.A mechanism for DNA-PK activation requiring unique contributions from each strand of a DNA terminus and implications for microhomology-mediated nonhomologous DNA end joining.V(D)J and immunoglobulin class switch recombinations: a paradigm to study the regulation of DNA end-joining.A non-leaky Artemis-deficient mouse that accurately models the human severe combined immune deficiency phenotype, including resistance to hematopoietic stem cell transplantation.
P2860
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P2860
The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The DNA-dependent protein kina ...... lation sites in human Artemis.
@ast
The DNA-dependent protein kina ...... lation sites in human Artemis.
@en
The DNA-dependent protein kina ...... lation sites in human Artemis.
@nl
type
label
The DNA-dependent protein kina ...... lation sites in human Artemis.
@ast
The DNA-dependent protein kina ...... lation sites in human Artemis.
@en
The DNA-dependent protein kina ...... lation sites in human Artemis.
@nl
altLabel
The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis
@en
prefLabel
The DNA-dependent protein kina ...... lation sites in human Artemis.
@ast
The DNA-dependent protein kina ...... lation sites in human Artemis.
@en
The DNA-dependent protein kina ...... lation sites in human Artemis.
@nl
P2093
P2860
P356
P1476
The DNA-dependent protein kina ...... lation sites in human Artemis.
@en
P2093
Doris Niewolik
Klaus Schwarz
Michael R Lieber
Ulrich Pannicke
P2860
P304
P356
10.1074/JBC.M507113200
P407
P577
2005-10-07T00:00:00Z