Toward high-resolution homology modeling of antibody Fv regions and application to antibody-antigen docking - Wikidata - wikimedia - TriplyDB

Toward high-resolution homology modeling of antibody Fv regions and application to antibody-antigen docking

Toward high-resolution homology modeling of antibody Fv regions and application to antibody-antigen docking

http://www.wikidata.org/entity/Q24603390

about

Antibody modeling assessment II. Structures and models SnugDock: paratope structural optimization during antibody-antigen docking compensates for errors in antibody homology models Putative bioactive motif of tritrpticin revealed by an antibody with biological receptor-like properties Serverification of molecular modeling applications: the Rosetta Online Server that Includes Everyone (ROSIE)Improving the accuracy of the structure prediction of the third hypervariable loop of the heavy chains of antibodies Antibody structure determination using a combination of homology modeling, energy-based refinement, and loop prediction.Antibody humanization by structure-based computational protein design.PyRosetta: a script-based interface for implementing molecular modeling algorithms using Rosetta A benchmark testing ground for integrating homology modeling and protein docking.ABodyBuilder: Automated antibody structure prediction with data-driven accuracy estimation.Automated protein structure modeling with SWISS-MODEL Workspace and the Protein Model Portal.A novel antibody humanization method based on epitopes scanning and molecular dynamics simulation Accuracy of protein-protein binding sites in high-throughput template-based modeling.OptCDR: a general computational method for the design of antibody complementarity determining regions for targeted epitope binding.Anti-non-Gal-specific combination treatment with an anti-idiotypic Ab and an inhibitory small molecule mitigates the xenoantibody response.Generation of monoclonal pan-hemagglutinin antibodies for the quantification of multiple strains of influenza.Disjoint combinations profiling (DCP): a new method for the prediction of antibody CDR conformation from sequence Near-native protein loop sampling using nonparametric density estimation accommodating sparcity.Computational docking of antibody-antigen complexes, opportunities and pitfalls illustrated by influenza hemagglutinin.MAPs: a database of modular antibody parts for predicting tertiary structures and designing affinity matured antibodies Analysis and modeling of the variable region of camelid single-domain antibodies.The origin of CDR H3 structural diversity.Selection of a human butyrylcholinesterase-like antibody single-chain variable fragment resistant to AChE inhibitors from a phage library expressed in E. coli.Structural basis for the recognition in an idiotype-anti-idiotype antibody complex related to celiac disease.OptMAVEn--a new framework for the de novo design of antibody variable region models targeting specific antigen epitopes.Examining variable domain orientations in antigen receptors gives insight into TCR-like antibody design.IBC's 22nd Annual Antibody Engineering and 9th Annual Antibody Therapeutics International Conferences and the 2011 Annual Meeting of The Antibody Society, December 5-8, 2011, San Diego, CA.Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc.Computer-aided antibody design.Conformer selection and induced fit in flexible backbone protein-protein docking using computational and NMR ensembles.Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.RosettaAntibody: antibody variable region homology modeling server.Humanization of high-affinity antibodies targeting glypican-3 in hepatocellular carcinoma Synergistic Neutralization of Pertussis Toxin by a Bispecific Antibody In Vitro and In Vivo Functional screening for anti-CMV biologics identifies a broadly neutralizing epitope of an essential envelope protein Computational design of an epitope-specific Keap1 binding antibody using hotspot residues grafting and CDR loop swapping.Challenges and advances in computational docking: 2009 in review.Sphinx: merging knowledge-based and ab initio approaches to improve protein loop prediction.Antigen recognition by antibody C836 through adjustment of V(L)/V(H) packing.

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Toward high-resolution homology modeling of antibody Fv regions and application to antibody-antigen docking

http://www.wikidata.org/entity/Q24603390

description

2009 nî lūn-bûn

@nan

2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Toward high-resolution homolog ...... on to antibody-antigen docking

@ast

Toward high-resolution homolog ...... on to antibody-antigen docking

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Toward high-resolution homolog ...... on to antibody-antigen docking

@nl

type

label

Toward high-resolution homolog ...... on to antibody-antigen docking

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Toward high-resolution homolog ...... on to antibody-antigen docking

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Toward high-resolution homolog ...... on to antibody-antigen docking

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prefLabel

Toward high-resolution homolog ...... on to antibody-antigen docking

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Toward high-resolution homolog ...... on to antibody-antigen docking

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Toward high-resolution homolog ...... on to antibody-antigen docking

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Toward high-resolution homolog ...... on to antibody-antigen docking

@en

P2093

Aroop Sircar

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Arvind Sivasubramanian

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Sidhartha Chaudhury

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P2860

The Protein Data Bank

Probing a protein-protein interaction by in vitro evolution

Amino acid substitution matrices from protein blocks

Improved side-chain modeling for protein-protein docking

Native protein sequences are close to optimal for their structures

Basic local alignment search tool

Canonical antigen-binding loop structures in immunoglobulins: more structures, more canonical classes?

Major antigen-induced domain rearrangements in an antibody

Structural consequences of humanizing an antibody

VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs

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497-514

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scholarly article

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2792029

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10.1002/PROT.22309

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2

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74

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Jeffrey J. Gray

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2009-02-01T00:00:00Z

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23629229

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19062174

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2909601

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