Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes
about
Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHRDeregulated expression of PAX5 in medulloblastomaBackfoot is a novel homeobox gene expressed in the mesenchyme of developing hind limbIn vivo amplification of the PAX3-FKHR and PAX7-FKHR fusion genes in alveolar rhabdomyosarcomaAnalysis of human muscle stem cells reveals a differentiation-resistant progenitor cell population expressing Pax7 capable of self-renewal.Sox5 functions as a fate switch in medaka pigment cell developmentIntegrated functions of Pax3 and Pax7 in the regulation of proliferation, cell size and myogenic differentiation.An engineered PAX3-KRAB transcriptional repressor inhibits the malignant phenotype of alveolar rhabdomyosarcoma cells harboring the endogenous PAX3-FKHR oncogeneEmbryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3Pax3 inhibits myogenic differentiation of cultured myoblast cells.Analysis of the mouse Splotch-delayed mutation indicates that the Pax-3 paired domain can influence homeodomain DNA-binding activityGene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma.Methylation alterations of the MyoD1 upstream region are predictive of subclassification of human rhabdomyosarcomas.Molecular features of a human rhabdomyosarcoma cell line with spontaneous metastatic progressioncDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene.Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma.DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5).Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor alpha receptor.Identification and characterization of subpopulations of Pax3 and Pax7 expressing cells in developing chick somites and limb budsC-terminal activating and inhibitory domains determine the transactivation potential of BSAP (Pax-5), Pax-2 and Pax-8.DNA methylation and developmental genes in lymphomagenesis--more questions than answers?Cloning and characterization of the human PAX7 promoter.PAX3 and PAX7 exhibit conserved cis-acting transcription repression domains and utilize a common gain of function mechanism in alveolar rhabdomyosarcoma.Pax3 is essential for skeletal myogenesis and the expression of Six1 and Eya2.Zebrafish Pax9 encodes two proteins with distinct C-terminal transactivating domains of different potency negatively regulated by adjacent N-terminal sequences.PAX7 target genes are globally repressed in facioscapulohumeral muscular dystrophy skeletal muscle.Cross-talk between the paired domain and the homeodomain of Pax3: DNA binding by each domain causes a structural change in the other domain, supporting interdependence for DNA Binding.AmphiPax3/7, an amphioxus paired box gene: insights into chordate myogenesis, neurogenesis, and the possible evolutionary precursor of definitive vertebrate neural crest.
P2860
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P2860
Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes
description
1994 nî lūn-bûn
@nan
1994 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Molecular cloning and characte ...... normal and neoplastic myocytes
@ast
Molecular cloning and characte ...... normal and neoplastic myocytes
@en
Molecular cloning and characte ...... normal and neoplastic myocytes
@nl
type
label
Molecular cloning and characte ...... normal and neoplastic myocytes
@ast
Molecular cloning and characte ...... normal and neoplastic myocytes
@en
Molecular cloning and characte ...... normal and neoplastic myocytes
@nl
prefLabel
Molecular cloning and characte ...... normal and neoplastic myocytes
@ast
Molecular cloning and characte ...... normal and neoplastic myocytes
@en
Molecular cloning and characte ...... normal and neoplastic myocytes
@nl
P2860
P50
P356
P1476
Molecular cloning and characte ...... normal and neoplastic myocytes
@en
P2093
P2860
P304
P356
10.1093/NAR/22.22.4574
P407
P577
1994-11-11T00:00:00Z