Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3 - Wikidata - wikimedia - TriplyDB

Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3

Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3

http://www.wikidata.org/entity/Q34091728

about

IRIZIO: a novel gene cooperating with PAX3-FOXO1 in alveolar rhabdomyosarcoma (ARMS)PAX3-FOXO1 fusion gene in rhabdomyosarcoma FOXOs, cancer and regulation of apoptosis The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.Thrombin regulates the metastatic potential of human rhabdomyosarcoma cells: distinct role of PAR1 and PAR3 signaling.FOXO1: a potential target for human diseases Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma.Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors.A Drosophila model of the rhabdomyosarcoma initiator PAX7-FKHR.The many forks in FOXO's road.Single-channel quantitative multiplex reverse transcriptase-polymerase chain reaction for large numbers of gene products differentiates nondemented from neuropathological Alzheimer's disease.The PAX3-FOXO1 fusion protein present in rhabdomyosarcoma interferes with normal FOXO activity and the TGF-β pathway.Combinatorial transcriptional interaction within the cardiac neural crest: a pair of HANDs in heart formation.Childhood rhabdomyosarcoma: recent advances and prospective views.Probing for a deeper understanding of rhabdomyosarcoma: insights from complementary model systems.PAX3-FOXO1 controls expression of the p57Kip2 cell-cycle regulator through degradation of EGR1.FOXO1a acts as a selective tumor suppressor in alveolar rhabdomyosarcoma.FoxO tumor suppressors and BCR-ABL-induced leukemia: a matter of evasion of apoptosis.FOXO factors: a matter of life and death.Alveolar rhabdomyosarcoma - The molecular drivers of PAX3/7-FOXO1-induced tumorigenesis Pigmentation PAX-ways: the role of Pax3 in melanogenesis, melanocyte stem cell maintenance, and disease Advances in pediatric rhabdomyosarcoma characterization and disease model development.Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.Caveolins in rhabdomyosarcoma Rhabdomyosarcomas: an overview on the experimental animal models.In vivo and in vitro disease modeling with CRISPR/Cas9.PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis.Picropodophyllin (PPP) is a potent rhabdomyosarcoma growth inhibitor both in vitro and in vivo A review of soft-tissue sarcomas: translation of biological advances into treatment measures.

P2860

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P2860

Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3

http://www.wikidata.org/entity/Q34091728

description

2001 nî lūn-bûn

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2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2001 թվականի փետրվարին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

Embryonic expression of the tu ...... evelopmental functions of Pax3

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Embryonic expression of the tu ...... evelopmental functions of Pax3

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Embryonic expression of the tu ...... evelopmental functions of Pax3

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Embryonic expression of the tu ...... evelopmental functions of Pax3

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Embryonic expression of the tu ...... evelopmental functions of Pax3

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Embryonic expression of the tu ...... evelopmental functions of Pax3

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Embryonic expression of the tu ...... evelopmental functions of Pax3

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Embryonic expression of the tu ...... evelopmental functions of Pax3

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Embryonic expression of the tu ...... evelopmental functions of Pax3

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Embryonic expression of the tu ...... evelopmental functions of Pax3

@en

P2093

G D Shelton

http://www.w3.org/2001/XMLSchema#string

K C Arden

http://www.w3.org/2001/XMLSchema#string

M J Anderson

http://www.w3.org/2001/XMLSchema#string

W K Cavenee

http://www.w3.org/2001/XMLSchema#string

P2860

The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes

Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily

Mechanisms of p53 loss in human sarcomas.

Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma.

Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma.

Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma.

Pax3 modulates expression of the c-Met receptor during limb muscle development.

Molecular biology of lymphoid malignancies.

The alveolar rhabdomyosarcoma PAX3/FKHR fusion protein is a transcriptional activator.

P304

1589-1594

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scholarly article

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10.1073/PNAS.98.4.1589

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4

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98

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2001-02-01T00:00:00Z

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12158367

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11171995

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29301

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