Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling - Wikidata - wikimedia - TriplyDB

Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling

Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling

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Discoidin Domain Receptors: Potential Actors and Targets in Cancer Dynamic interplay between adhesion surfaces in carcinomas: Cell-cell and cell-matrix crosstalk Discoidin domain receptor 1 (DDR1) kinase as target for structure-based drug discovery The fibrosis-cell death axis in heart failure Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants The Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors.Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity.The Regulation of Matrix Metalloproteinase Expression and the Role of Discoidin Domain Receptor 1/2 Signalling in Zoledronate-treated PC3 Cells.Discoidin domain receptors in disease.Normal activation of discoidin domain receptor 1 mutants with disulfide cross-links, insertions, or deletions in the extracellular juxtamembrane region: mechanistic implications Endocytosis of collagen by hepatic stellate cells regulates extracellular matrix dynamics.Discoidin domain receptor 1 contributes to tumorigenesis through modulation of TGFBI expression.Vitamin a deficiency and alterations in the extracellular matrix.Collagen inhibitory peptide R1R2 mediates vascular remodeling by decreasing inflammation and smooth muscle cell activation Clostridium sordellii genome analysis reveals plasmid localized toxin genes encoded within pathogenicity loci Novel insights into the function and dynamics of extracellular matrix in liver fibrosis.Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor.Role of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence.The genome-wide role of HSF-1 in the regulation of gene expression in Caenorhabditis elegans The C. elegans Discoidin Domain Receptor DDR-2 Modulates the Met-like RTK-JNK Signaling Pathway in Axon Regeneration Discoidin Domain Receptor-1 Regulates Calcific Extracellular Vesicle Release in Vascular Smooth Muscle Cell Fibrocalcific Response via Transforming Growth Factor-β Signaling.HANAC Syndrome Col4a1 Mutation Causes Neonate Glomerular Hyperpermeability and Adult Glomerulocystic Kidney Disease.Polymerase delta-interacting protein 2 regulates collagen accumulation via activation of the Akt/mTOR pathway in vascular smooth muscle cells.Prognostic significance of discoidin domain receptor 2 (DDR2) expression in ovarian cancer.Discoidin domain receptor 1 is a novel transcriptional target of ZEB1 in breast epithelial cells undergoing H-Ras-induced epithelial to mesenchymal transition.The BRAF(V600E) inhibitor, PLX4032, increases type I collagen synthesis in melanoma cells Tyrosine kinase discoidin domain receptors DDR1 and DDR2 are coordinately deregulated in triple-negative breast cancer.Mesenchymal Stem Cell-Induced DDR2 Mediates Stromal-Breast Cancer Interactions and Metastasis Growth.Glycosylation at Asn211 regulates the activation state of the discoidin domain receptor 1 (DDR1).The pathobiology of collagens in glioma.Discoidin domain receptors: a proteomic portrait.Discoidin domain receptor 2 signaling networks and therapy in lung cancer.Quantitative proteomic analyses of Schistosoma japonicum in response to artesunate.Synthesis and biological evaluation of novel dasatinib analogues as potent DDR1 and DDR2 kinase inhibitors.Contribution of collagen adhesion receptors to tissue fibrosis.Exploiting receptor tyrosine kinase co-activation for cancer therapy.Defective Ca(2+) binding in a conserved binding site causes incomplete N-glycan processing and endoplasmic reticulum trapping of discoidin domain receptors.The Diacetyl-Exposed Human Airway Epithelial Secretome: New Insights into Flavoring-Induced Airways Disease.Melanocytes from the outer root sheath of human hair and epidermal melanocytes display improved melanotic features in the niche provided by cGEL, oligomer-cross-linked gelatin-based hydrogel.Oligomerization of DDR1 ECD affects receptor-ligand binding.

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Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling

http://www.wikidata.org/entity/Q24604831

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2013 nî lūn-bûn

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Journal of Biological Chemistry

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Anjum Sohail

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Cosmin Mihai

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Hsueh-Liang Fu

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Kiran V Mahasenan

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Malika Kumarasiri

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Rafael Fridman

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Rajeshwari R Valiathan

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Richard Arkwright

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Shahriar Mobashery

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P2860

Discoidin domain receptors promote α1β1- and α2β1-integrin mediated cell adhesion to collagen by enhancing integrin activation

Crystallographic insight into collagen recognition by discoidin domain receptor 2

Pinpointing phosphotyrosine-dependent interactions downstream of the collagen receptor DDR1

Collagen binding specificity of the discoidin domain receptors: binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1

The discoidin domain receptor tyrosine kinases are activated by collagen

Tyrosine 740 phosphorylation of discoidin domain receptor 2 by Src stimulates intramolecular autophosphorylation and Shc signaling complex formation

Structural basis of the collagen-binding mode of discoidin domain receptor 2

A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain

Comprehensive molecular portraits of human breast tumours

Discoidin domain receptor 2 mediates tumor cell cycle arrest induced by fibrillar collagen

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