Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363
about
Novel lipid droplet-associated serine hydrolase regulates macrophage cholesterol mobilizationChemoproteomic discovery of AADACL1 as a regulator of human platelet activation.Lipid droplets: size matters.Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores.The metabolic serine hydrolases and their functions in mammalian physiology and disease.Perilipin1 deficiency in whole body or bone marrow-derived cells attenuates lesions in atherosclerosis-prone mice.Micro RNA-124a regulates lipolysis via adipose triglyceride lipase and comparative gene identification 58.Cytoskeleton disruption in J774 macrophages: consequences for lipid droplet formation and cholesterol fluxActive autophagy but not lipophagy in macrophages with defective lipolysis.Identification of a novel intracellular cholesteryl ester hydrolase (carboxylesterase 3) in human macrophages: compensatory increase in its expression after carboxylesterase 1 silencingCholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null miceLipid droplet-associated proteins in atherosclerosis (Review).Genetics of cholesterol efflux.Effects of toxicologically relevant xenobiotics and the lipid-derived electrophile 4-hydroxynonenal on macrophage cholesterol efflux: silencing carboxylesterase 1 has paradoxical effects on cholesterol uptake and efflux.Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism.Carboxylesterases in lipid metabolism: from mouse to human.A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis.Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages.Interaction of the serine hydrolase KIAA1363 with organophosphorus agents: Evaluation of potency and kinetics.Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages.Neutral cholesterol ester hydrolases in macrophages: still a matter of debate.An activity-dependent proximity ligation platform for spatially resolved quantification of active enzymes in single cells.Global inactivation of carboxylesterase 1 (Ces1/Ces1g) protects against atherosclerosis in Ldlr -/- mice.Silencing Carboxylesterase 1 in Human THP-1 Macrophages Perturbs Genes Regulated by PPARg/RXR and RAR/RXR: Downregulation of CYP27A1-LXRα Signaling.
P2860
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P2860
Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363
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2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-hans
2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Cholesteryl ester hydrolase ac ...... n macrophages lacking KIAA1363
@ast
Cholesteryl ester hydrolase ac ...... n macrophages lacking KIAA1363
@en
Cholesteryl ester hydrolase ac ...... n macrophages lacking KIAA1363
@nl
type
label
Cholesteryl ester hydrolase ac ...... n macrophages lacking KIAA1363
@ast
Cholesteryl ester hydrolase ac ...... n macrophages lacking KIAA1363
@en
Cholesteryl ester hydrolase ac ...... n macrophages lacking KIAA1363
@nl
prefLabel
Cholesteryl ester hydrolase ac ...... n macrophages lacking KIAA1363
@ast
Cholesteryl ester hydrolase ac ...... n macrophages lacking KIAA1363
@en
Cholesteryl ester hydrolase ac ...... n macrophages lacking KIAA1363
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Cholesteryl ester hydrolase ac ...... n macrophages lacking KIAA1363
@en
P2093
Adelheid Kratzer
Benjamin Cravatt
Gerhard M Kostner
Harald Koefeler
Kyle P Chiang
Marlene Buchebner
Nora Rathke
Prakash G Chandak
Sanja Levak-Frank
Thomas Pfeifer
P2860
P304
P3181
P356
10.1194/JLR.M004259
P407
P50
P577
2010-10-01T00:00:00Z