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Altered stability of pulmonary surfactant in SP-C-deficient mice

Altered stability of pulmonary surfactant in SP-C-deficient mice

http://www.wikidata.org/entity/Q24626562

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Genetic complexity of the human innate host defense molecules, surfactant protein A1 (SP-A1) and SP-A2--impact on function Genetic complexity of the human surfactant-associated proteins SP-A1 and SP-A2 The role of surfactant in asthma Interstitial lung disease in children -- genetic background and associated phenotypes.Involvement of cathepsin H in the processing of the hydrophobic surfactant-associated protein C in type II pneumocytes GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression Genetic disorders of surfactant dysfunction Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease Pulmonary surfactant pathophysiology: current models and open questions Superficial disposition of the N-terminal region of the surfactant protein SP-C and the absence of specific SP-B-SP-C interactions in phospholipid bilayers SFTA2--a novel secretory peptide highly expressed in the lung--is modulated by lipopolysaccharide but not hyperoxia Biosynthesis of surfactant protein C (SP-C). Sorting of SP-C proprotein involves homomeric association via a signal anchor domain Essential and mutually compensatory roles of {alpha}-mannosidase II and {alpha}-mannosidase IIx in N-glycan processing in vivo in mice Essential roles of ECAT15-2/Dppa2 in functional lung development The transcription factor gene Nfib is essential for both lung maturation and brain development Expression and Localization of Lung Surfactant Proteins in Human Testis Role of secretoglobin 3A2 in lung development.Disruption of sorting nexin 5 causes respiratory failure associated with undifferentiated alveolar epithelial type I cells in mice.Increased phosphatidylcholine production but disrupted glycogen metabolism in fetal type II cells of mice that overexpress CTP:phosphocholine cytidylyltransferase.Effect of SP-B peptides on the uptake of liposomes by alveolar cells.Nedd4-2-mediated ubiquitination facilitates processing of surfactant protein-C Functional importance of the NH2-terminal insertion sequence of lung surfactant protein B.LPCAT1 regulates surfactant phospholipid synthesis and is required for transitioning to air breathing in mice.Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia Surfactant protein-C promoter variants associated with neonatal respiratory distress syndrome reduce transcription Keeping lung surfactant where it belongs: protein regulation of two-dimensional viscosity Alveolar type II cells possess the capability of initiating lung tumor development Characterization and classification of ATP-binding cassette transporter ABCA3 mutants in fatal surfactant deficiency.ABCA3-mediated choline-phospholipids uptake into intracellular vesicles in A549 cells.Heterozygosity for ABCA3 mutations modifies the severity of lung disease associated with a surfactant protein C gene (SFTPC) mutation.Surfactant proteins as genetic determinants of multifactorial pulmonary diseases.Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin The Hsp90 cochaperone p23 is essential for perinatal survival.Role of marsupial tammar wallaby milk in lung maturation of pouch young From birds to humans: new concepts on airways relative to alveolar surfactant.Surfactant therapy for respiratory distress syndrome in premature neonates: a comparative review.Role of phosphocholine cytidylyltransferase alpha in lung development.Lipid-protein interactions alter line tensions and domain size distributions in lung surfactant monolayers Environmental Pollutant Ozone Causes Damage to Lung Surfactant Protein B (SP-B).

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P2860

Altered stability of pulmonary surfactant in SP-C-deficient mice

http://www.wikidata.org/entity/Q24626562

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Altered stability of pulmonary surfactant in SP-C-deficient mice

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Altered stability of pulmonary surfactant in SP-C-deficient mice

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Altered stability of pulmonary surfactant in SP-C-deficient mice

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Altered stability of pulmonary surfactant in SP-C-deficient mice

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Altered stability of pulmonary surfactant in SP-C-deficient mice

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Altered stability of pulmonary surfactant in SP-C-deficient mice

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Altered stability of pulmonary surfactant in SP-C-deficient mice

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Altered stability of pulmonary surfactant in SP-C-deficient mice

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Altered stability of pulmonary surfactant in SP-C-deficient mice

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Proceedings of the National Academy of Sciences of the United States of America

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Altered stability of pulmonary surfactant in SP-C-deficient mice

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P2093

C L Na

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G F Ross

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J A Whitsett

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M Ikegami

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P2860

Altered surfactant homeostasis and alveolar type II cell morphology in mice lacking surfactant protein D

A mutation in the surfactant protein C gene associated with familial interstitial lung disease

Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice.

Tumor necrosis factor-alpha inhibits expression of pulmonary surfactant protein

Altered surfactant function and structure in SP-A gene targeted mice.

The pulmonary surfactant system: biochemical and clinical aspects.

Effect of recombinant SP-C surfactant in a porcine lavage model of acute lung injury.

Inhaled flunisolide for acute severe asthma.

Input impedance and peripheral inhomogeneity of dog lungs.

Effects of lung surfactant proteolipid SP-C on the organization of model membrane lipids: a fluorescence study.

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