Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS
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Emerging preclinical pharmacological targets for Parkinson's diseaseNeurobiological Insights from mGlu Receptor Allosteric Modulation.Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7Targeting metabotropic glutamate receptors for novel treatments of schizophrenia.Metabotropic glutamate receptor 1 splice variants mGluR1a and mGluR1b combine in mGluR1a/b dimers in vivoCooperative signaling between homodimers of metabotropic glutamate receptors 1 and 5Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders.Molecular Insights into Metabotropic Glutamate Receptor Allosteric ModulationDevelopment and Antiparkinsonian Activity of VU0418506, a Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor 4 Homomers without Activity at mGlu2/4 Heteromers.Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate ReceptorsProgress toward advanced understanding of metabotropic glutamate receptors: structure, signaling and therapeutic indicationsGroup III metabotropic glutamate receptors: pharmacology, physiology and therapeutic potential.Quantitative analysis of receptor allosterism and its implication for drug discovery.Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells.Organization and functions of mGlu and GABAB receptor complexes.Allosteric Modulation of GPCRs: New Insights and Potential Utility for Treatment of Schizophrenia and Other CNS Disorders.Group 1 metabotropic glutamate receptors 1 and 5 form a protein complex in mouse hippocampus and cortex.Co-operative binding assay for the characterization of mGlu4 allosteric modulators.Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors.Class C G protein-coupled receptors: reviving old couples with new partners.Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation.Structural biology of GABAB receptor.Biased allosteric agonism and modulation of metabotropic glutamate receptor 5: Implications for optimizing preclinical neuroscience drug discovery.HTS-compatible FRET-based conformational sensors clarify membrane receptor activation.Differential Pharmacology and Binding of mGlu2 Receptor Allosteric Modulators.Group II Metabotropic Glutamate Receptors: Role in Pain Mechanisms and Pain Modulation
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P2860
Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS
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2014 nî lūn-bûn
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2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Selective actions of novel all ...... glutamate receptors in the CNS
@ast
Selective actions of novel all ...... glutamate receptors in the CNS
@en
Selective actions of novel all ...... glutamate receptors in the CNS
@nl
type
label
Selective actions of novel all ...... glutamate receptors in the CNS
@ast
Selective actions of novel all ...... glutamate receptors in the CNS
@en
Selective actions of novel all ...... glutamate receptors in the CNS
@nl
prefLabel
Selective actions of novel all ...... glutamate receptors in the CNS
@ast
Selective actions of novel all ...... glutamate receptors in the CNS
@en
Selective actions of novel all ...... glutamate receptors in the CNS
@nl
P2093
P2860
P50
P3181
P1476
Selective actions of novel all ...... glutamate receptors in the CNS
@en
P2093
Kari A Johnson
Meredith J Noetzel
Nidhi Jalan-Sakrikar
Rocio Zamorano
P2860
P3181
P356
10.1523/JNEUROSCI.1129-13.2014
P407
P577
2014-01-01T00:00:00Z