Co-operative binding assay for the characterization of mGlu4 allosteric modulators.

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Re-exploring the N-phenylpicolinamide derivatives to develop mGlu4 ligands with improved affinity and in vitro microsomal stability.Differential Pharmacology and Binding of mGlu2 Receptor Allosteric Modulators.

P2860

Q35964194-13156454-6D1A-4E1E-A82D-9FDB64CAF42F Q52653356-CE120C69-2A1F-4794-BD78-1972EE1B3ACA

P2860

Co-operative binding assay for the characterization of mGlu4 allosteric modulators.

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http://www.wikidata.org/entity/Q41887461

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2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Co-operative binding assay for the characterization of mGlu4 allosteric modulators.

@en

type

Item

label

Co-operative binding assay for the characterization of mGlu4 allosteric modulators.

@en

prefLabel

Co-operative binding assay for the characterization of mGlu4 allosteric modulators.

@en

P1476

Co-operative binding assay for the characterization of mGlu4 allosteric modulators

@en

P2093

Anna-Liisa Brownell

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Bakhos Tannous

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Darshini Kuruppu

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Kun-Eek Kil

http://www.w3.org/2001/XMLSchema#string

Zhaoda Zhang

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P2860

Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS

Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs)

Allosteric modulation of group III metabotropic glutamate receptor 4: a potential approach to Parkinson's disease treatment

The ensemble nature of allostery

Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.

Determining allosteric modulator mechanism of action: integration of radioligand binding and functional assay data.

Ion dependence of ligand binding to metabotropic glutamate receptors.

Allosteric binding sites on cell-surface receptors: novel targets for drug discovery.

Orthosteric versus allosteric GPCR activation: the great challenge of group-III mGluRs.

Protective effect of metabotropic glutamate mGluR5 receptor elimination in a 6-hydroxydopamine model of Parkinson's disease.

P304

142-148

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scholarly article

P356

10.1016/J.NEUROPHARM.2015.05.017

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P478

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Pekka K Poutiainen

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2015-05-27T00:00:00Z

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P698

26025660

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P932

4537392

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Co-operative binding assay for the characterization of mGlu4 allosteric modulators.

about

P2860

P2860

Co-operative binding assay for the characterization of mGlu4 allosteric modulators.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P478

P50

P577

P698

P932