Standard opioid agonists activate heteromeric opioid receptors: evidence for morphine and [d-Ala(2)-MePhe(4)-Glyol(5)]enkephalin as selective μ-δ agonists
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Clinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeysThe δ opioid receptor agonist SNC80 selectively activates heteromeric μ-δ opioid receptorsBasic Pharmacological and Structural Evidence for Class A G-Protein-Coupled Receptor HeteromerizationPutative kappa opioid heteromers as targets for developing analgesics free of adverse effects.N-naphthoyl-beta-naltrexamine (NNTA), a highly selective and potent activator of μ/kappa-opioid heteromersIdentification of a μ-δ opioid receptor heteromer-biased agonist with antinociceptive activity.Heteromers of μ-δ opioid receptors: new pharmacology and novel therapeutic possibilities.Analgesic synergy between opioid and α2 -adrenoceptorsLigand requirements for involvement of PKCε in synergistic analgesic interactions between spinal μ and δ opioid receptors.Heteromerization of the μ- and δ-opioid receptors produces ligand-biased antagonism and alters μ-receptor traffickingEngineering endomorphin drugs: state of the art.Opioid activity of spinally selective analogues of N-naphthoyl-β-naltrexamine in HEK-293 cells and mice.Combined Effects of Bee Venom Acupuncture and Morphine on Oxaliplatin-Induced Neuropathic Pain in Mice.Heteroatom analogues of hydrocodone: synthesis and biological activityReceptor and channel heteromers as pain targets.Association of OPRD1 polymorphisms with heroin dependence in a large case-control series.Pharmacological Profiles of Oligomerized μ-Opioid Receptors.Molecular Perspectives for mu/delta Opioid Receptor Heteromers as Distinct, Functional ReceptorsA κ Opioid Pharmacophore Becomes a Spinally Selective κ-δ Agonist When Modified with a Basic Extender Arm.An immunocytochemical-derived correlate for evaluating the bridging of heteromeric mu-delta opioid protomers by bivalent ligands.Basic/Translational Development of Forthcoming Opioid- and Nonopioid-Targeted Pain Therapeutics.The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability.In vitro and in vivo characterisation of the bifunctional MOP/DOP ligand UFP-505.Pain Therapy Guided by Purpose and Perspective in Light of the Opioid Epidemic.
P2860
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P2860
Standard opioid agonists activate heteromeric opioid receptors: evidence for morphine and [d-Ala(2)-MePhe(4)-Glyol(5)]enkephalin as selective μ-δ agonists
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Standard opioid agonists activ ...... alin as selective μ-δ agonists
@ast
Standard opioid agonists activ ...... alin as selective μ-δ agonists
@en
Standard opioid agonists activ ...... alin as selective μ-δ agonists
@nl
type
label
Standard opioid agonists activ ...... alin as selective μ-δ agonists
@ast
Standard opioid agonists activ ...... alin as selective μ-δ agonists
@en
Standard opioid agonists activ ...... alin as selective μ-δ agonists
@nl
prefLabel
Standard opioid agonists activ ...... alin as selective μ-δ agonists
@ast
Standard opioid agonists activ ...... alin as selective μ-δ agonists
@en
Standard opioid agonists activ ...... alin as selective μ-δ agonists
@nl
P2093
P2860
P921
P3181
P356
P1476
Standard opioid agonists activ ...... alin as selective μ-δ agonists
@en
P2093
Ajay S Yekkirala
Alexander E Kalyuzhny
Philip S Portoghese
P2860
P304
P3181
P356
10.1021/CN9000236
P407
P577
2010-02-17T00:00:00Z