Inhibition of cellular DNA polymerase alpha and human cytomegalovirus-induced DNA polymerase by the triphosphates of 9-(2-hydroxyethoxymethyl)guanine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine
about
A human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphateGene therapy for carcinoma of the breast: Genetic toxinsMechanism of ganciclovir-induced chain termination revealed by resistant viral polymerase mutants with reduced exonuclease activityPhosphorylation of beta-D-ribosylbenzimidazoles is not required for activity against human cytomegalovirusA novel nonnucleoside inhibitor specifically targets cytomegalovirus DNA maturation via the UL89 and UL56 gene products.Activity of 9-(1,3-dihydroxy-2-propoxymethyl)guanine compared with that of acyclovir against human, monkey, and rodent cytomegalovirusesAcyclic guanosine analogs as inhibitors of human cytomegalovirusResistance of human cytomegalovirus to benzimidazole ribonucleosides maps to two open reading frames: UL89 and UL56Selective induction of toxicity to human cells expressing human immunodeficiency virus type 1 Tat by a conditionally cytotoxic adenovirus vector.Impact of 2-bromo-5,6-dichloro-1-beta-D-ribofuranosyl benzimidazole riboside and inhibitors of DNA, RNA, and protein synthesis on human cytomegalovirus genome maturation.Induction of Epstein-Barr virus kinases to sensitize tumor cells to nucleoside analoguesLobucavir is phosphorylated in human cytomegalovirus-infected and -uninfected cells and inhibits the viral DNA polymeraseA point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives.Antiviral therapy: current concepts and practicesMurine cytomegalovirus infection of mouse macrophages stimulates early expression of suppressor of cytokine signaling (SOCS)1 and SOCS3.Genomic localization, sequence analysis, and transcription of the putative human cytomegalovirus DNA polymerase gene.Human cytomegalovirus induces JC virus DNA replication in human fibroblasts.Two specific topoisomerase II inhibitors prevent replication of human cytomegalovirus DNA: an implied role in replication of the viral genome.Sequence and transcription analysis of the human cytomegalovirus DNA polymerase gene.Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymeraseCharacterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragmentsHuman herpesvirus 8-encoded thymidine kinase and phosphotransferase homologues confer sensitivity to ganciclovirIntranuclear accumulation of subgenomic noninfectious human cytomegalovirus DNA in infected cells in the presence of ganciclovir.Ganciclovir-resistant cytomegalovirus clinical isolates: mode of resistance to ganciclovir."The end of innocence" revisited: resistance of herpesviruses to antiviral drugs.Gene therapy with HSV1-sr39TK/GCV exhibits a stronger therapeutic efficacy than HSV1-TK/GCV in rat C6 glioma cells.
P2860
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P2860
Inhibition of cellular DNA polymerase alpha and human cytomegalovirus-induced DNA polymerase by the triphosphates of 9-(2-hydroxyethoxymethyl)guanine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine
description
1985 nî lūn-bûn
@nan
1985 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1985 թվականի մարտին հրատարակված գիտական հոդված
@hy
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
name
Inhibition of cellular DNA pol ...... ydroxy-2-propoxymethyl)guanine
@ast
Inhibition of cellular DNA pol ...... ydroxy-2-propoxymethyl)guanine
@en
Inhibition of cellular DNA pol ...... ydroxy-2-propoxymethyl)guanine
@nl
type
label
Inhibition of cellular DNA pol ...... ydroxy-2-propoxymethyl)guanine
@ast
Inhibition of cellular DNA pol ...... ydroxy-2-propoxymethyl)guanine
@en
Inhibition of cellular DNA pol ...... ydroxy-2-propoxymethyl)guanine
@nl
prefLabel
Inhibition of cellular DNA pol ...... ydroxy-2-propoxymethyl)guanine
@ast
Inhibition of cellular DNA pol ...... ydroxy-2-propoxymethyl)guanine
@en
Inhibition of cellular DNA pol ...... ydroxy-2-propoxymethyl)guanine
@nl
P2093
P2860
P1433
P1476
Inhibition of cellular DNA pol ...... ydroxy-2-propoxymethyl)guanine
@en
P2093
P2860
P304
P407
P577
1985-03-01T00:00:00Z