A new nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl]methyl]guanine, highly active in vitro against herpes simplex virus types 1 and 2
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Inhibition of cellular DNA polymerase alpha and human cytomegalovirus-induced DNA polymerase by the triphosphates of 9-(2-hydroxyethoxymethyl)guanine and 9-(1,3-dihydroxy-2-propoxymethyl)guanineCrystal structure of poxvirus thymidylate kinase: An unexpected dimerization has implications for antiviral therapyActivity of 9-(1,3-dihydroxy-2-propoxymethyl)guanine compared with that of acyclovir against human, monkey, and rodent cytomegalovirusesEffect of antiviral agents on replication of herpes simplex virus type 1 in brain culturesAntiherpesvirus activity of 9-(4-hydroxy-3-hydroxy-methylbut-1-yl)guanine (BRL 39123) in cell cultureEffects of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new antiherpesvirus compound, on synthesis of macromolecules in herpes simplex virus-infected cellsInhibition of human cytomegalovirus replication by 9-(1,3-dihydroxy-2-propoxymethyl)guanine alone and in combination with human interferonsUnique spectrum of activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]-guanine against herpesviruses in vitro and its mode of action against herpes simplex virus type 19-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine: a selective inhibitor of herpes group virus replicationAnti-herpesvirus activity of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanineActivity of 1-(2'-fluoro-2'-deoxy-beta-D-arabinofuranosyl)thymine against herpes simplex virus in cell cultures and rabbit eyesEffects of the nucleoside analog 2'-nor-2'-deoxyguanosine on human cytomegalovirus replicationEfficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine against primary and recrudescent genital herpes simplex virus type 2 infections in guinea pigsEnhanced efficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine in combination with beta-interferon against herpes simplex virus type 2 in miceGuidelines for preventing infectious complications among hematopoietic cell transplantation recipients: a global perspectiveControl of graft-versus-host disease with maintenance of the graft-versus-leukemia effect in a murine allogeneic transplant model using retrovirally transduced murine suicidal lymphocytes.Ganciclovir inhibits human adenovirus replication and pathogenicity in permissive immunosuppressed Syrian hamsters.Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on the acute local phase of herpes simplex virus-induced skin infections in mice and the establishment of latency.Acyclic guanosine analogs as substrates for varicella-zoster virus thymidine kinase.Comparison of the modes of antiviral action of 2'-nor-deoxyguanosine and its cyclic phosphate, 2'-nor-cyclic GMP.Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on human cytomegalovirus replication in vitro.Efficacy of 2'-nor-2'-deoxyguanosine treatment for orofacial herpes simplex virus type 1 skin infections in miceResistance of herpes simplex virus to 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine: physical mapping of drug synergism within the viral DNA polymerase locusExamination of the roles of transcription factor Sp1-binding sites and an octamer motif in trans induction of the herpes simplex virus thymidine kinase gene.Human cytomegalovirus-induced DNA polymerase and its interaction with the triphosphates of 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-methyluracil, -5-iodocytosine, and -5-methylcytosineSensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locusProlonged inhibitory effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine against replication of Epstein-Barr virus.A review of antiviral drugs and other compounds with activity against feline herpesvirus type 1Targeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene.Antiadenoviral effects of ganciclovir in types inducing keratoconjunctivitis by quantitative polymerase chain reaction methods.Kinetics of the interaction of monophosphates of the antiviral nucleosides 2'-fluoro-1-beta-D-arabinofuranosylpyrimidine and (E)-5-(2-bromovinyl)-2'-deoxyuridine with thymidylate kinases from Vero cells and herpes simplex virus types 1 and 2.Inhibition by ganciclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information.Relative activities of acyclovir and BW759 against Aujeszky's disease and equine rhinopneumonitis viruses.Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U.Phosphorylation of four acyclic guanosine analogs by herpes simplex virus type 2 thymidine kinase.Synergism among BIOLF-62, phosphonoformate, and other antiherpetic compounds.
P2860
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P2860
A new nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl]methyl]guanine, highly active in vitro against herpes simplex virus types 1 and 2
description
1982 nî lūn-bûn
@nan
1982 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1982 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1982年の論文
@ja
1982年論文
@yue
1982年論文
@zh-hant
1982年論文
@zh-hk
1982年論文
@zh-mo
1982年論文
@zh-tw
1982年论文
@wuu
name
A new nucleoside analog, 9-[[2 ...... es simplex virus types 1 and 2
@ast
A new nucleoside analog, 9-[[2 ...... es simplex virus types 1 and 2
@en
A new nucleoside analog, 9-[[2 ...... es simplex virus types 1 and 2
@nl
type
label
A new nucleoside analog, 9-[[2 ...... es simplex virus types 1 and 2
@ast
A new nucleoside analog, 9-[[2 ...... es simplex virus types 1 and 2
@en
A new nucleoside analog, 9-[[2 ...... es simplex virus types 1 and 2
@nl
prefLabel
A new nucleoside analog, 9-[[2 ...... es simplex virus types 1 and 2
@ast
A new nucleoside analog, 9-[[2 ...... es simplex virus types 1 and 2
@en
A new nucleoside analog, 9-[[2 ...... es simplex virus types 1 and 2
@nl
P2093
P2860
P1476
A new nucleoside analog, 9-[[2 ...... es simplex virus types 1 and 2
@en
P2093
B K Radatus
K K Ogilvie
K S Galloway
W L Kennell
P2860
P407
P577
1982-07-01T00:00:00Z