BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome
about
The Werner syndrome protein is distinguished from the Bloom syndrome protein by its capacity to tightly bind diverse DNA structuresHuman single-stranded DNA binding proteins are essential for maintaining genomic stabilityRECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progressionRif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replicationMHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCMFAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathwayHuman topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repairInteraction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndromeThe RecQ DNA helicases in DNA repairMore complexity to the Bloom's syndrome complexRMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stabilityFunctions and regulation of the multitasking FANCM family of DNA motor proteinsTelomere shortening in human diseasesStructure and Cellular Roles of the RMI Core Complex from the Bloom Syndrome DissolvasomeCrystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complexDefining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasomeStructural and mechanistic insight into Holliday-junction dissolution by Topoisomerase IIIα and RMI1Decatenation of DNA by the S. cerevisiae Sgs1-Top3-Rmi1 and RPA complex: a mechanism for disentangling chromosomes.Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvaseOligonucleotide/oligosaccharide-binding fold proteins: a growing family of genome guardiansInterplay between structure-specific endonucleases for crossover control during Caenorhabditis elegans meiosisLoss of RMI2 Increases Genome Instability and Causes a Bloom-Like SyndromeETAA1 acts at stalled replication forks to maintain genome integrityATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions.Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changesThe RTR Complex Partner RMI2 and the DNA Helicase RTEL1 Are Both Independently Involved in Preserving the Stability of 45S rDNA Repeats in Arabidopsis thaliana.The G-quadruplex ligand telomestatin impairs binding of topoisomerase IIIalpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cellsWRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3TOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei.Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA.Distinct roles of RECQ1 in the maintenance of genomic stability.Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiationIdentification of Trypanosoma brucei RMI1/BLAP75 homologue and its roles in antigenic variation.PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution.The dissolution of double Holliday junctions.Escherichia coli RecG functionally suppresses human Bloom syndrome phenotypesMus81 and Yen1 promote reciprocal exchange during mitotic recombination to maintain genome integrity in budding yeast.A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells.Role of replication protein A in double holliday junction dissolution mediated by the BLM-Topo IIIα-RMI1-RMI2 protein complex
P2860
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P2860
BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome
@ast
BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome
@en
BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome
@nl
type
label
BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome
@ast
BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome
@en
BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome
@nl
prefLabel
BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome
@ast
BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome
@en
BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome
@nl
P2093
P2860
P3181
P356
P1433
P1476
BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome
@en
P2093
Abdullah Mahmood Ali
Amom Ruhikanta Meetei
Chang-hu Du
Patrick Sung
Paul R Andreassen
Steven Raynard
Thiyam Ramsing Singh
Valeria Busygina
P2860
P304
P3181
P356
10.1101/GAD.1725108
P407
P577
2008-10-15T00:00:00Z