[Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier - Wikidata - wikimedia - TriplyDB

[Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier

[Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier

http://www.wikidata.org/entity/Q24652657

about

Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes Lateral membrane biogenesis in human bronchial epithelial cells requires 190-kDa ankyrin-G Where is the spike generator of the cochlear nerve? Voltage-gated sodium channels in the mouse cochlea.Spectrin-based skeleton as an actor in cell signaling Neurofascin assembles a specialized extracellular matrix at the axon initial segment Axon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron Polarity Channelopathies from mutations in the cardiac sodium channel protein complex Neuro-glial interactions at the nodes of Ranvier: implication in health and diseases Axon initial segments: diverse and dynamic neuronal compartments Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment.Decreased temporal precision of neuronal signaling as a candidate mechanism of auditory processing disorder AlphaII-spectrin is critical for cell adhesion and cell cycle Integrative biological analysis for neuropsychopharmacology Genetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia Study A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier Specific role of the truncated betaIV-spectrin Sigma6 in sodium channel clustering at axon initial segments and nodes of ranvier Nodes of Ranvier and axon initial segments are ankyrin G-dependent domains that assemble by distinct mechanisms A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments In vivo assembly of the axon initial segment in motor neurons Accumulation of phosphorylated I kappaB alpha and activated IKK in nodes of Ranvier.Disruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury.Axonal Membranes and Their Domains: Assembly and Function of the Axon Initial Segment and Node of Ranvier.Myelination and regional domain differentiation of the axon.FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.Organization and maintenance of molecular domains in myelinated axons Spectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration in Drosophila.Loss of beta-III spectrin leads to Purkinje cell dysfunction recapitulating the behavior and neuropathology of spinocerebellar ataxia type 5 in humans.Initiation of simple and complex spikes in cerebellar Purkinje cells.Mutant β-III spectrin causes mGluR1α mislocalization and functional deficits in a mouse model of spinocerebellar ataxia type 5.Transgene rescue identifies an essential function for Drosophila beta spectrin in the nervous system and a selective requirement for ankyrin-2-binding activity.Role of the axonal initial segment in psychiatric disorders: function, dysfunction, and intervention Beta-III spectrin mutation L253P associated with spinocerebellar ataxia type 5 interferes with binding to Arp1 and protein trafficking from the Golgi.Dominant-negative mutations in alpha-II spectrin cause West syndrome with severe cerebral hypomyelination, spastic quadriplegia, and developmental delay.Identification of a conserved ankyrin-binding motif in the family of sodium channel alpha subunits.Restricted growth of Schwann cells lacking Cajal bands slows conduction in myelinated nerves.Voltage-gated ion channels in the axon initial segment of human cortical pyramidal cells and their relationship with chandelier cells.Composition, assembly, and maintenance of excitable membrane domains in myelinated axons.Ankyrin-G and beta2-spectrin collaborate in biogenesis of lateral membrane of human bronchial epithelial cells.The fibroblast growth factor 14·voltage-gated sodium channel complex is a new target of glycogen synthase kinase 3 (GSK3).

P2860

9d8864a64e2d64df516605162cd2a65fa1a591f3

P248

Q24299734-7F611B89-9F12-4DA3-978B-227EB780D810 Q24306908-7CDA5ED3-1363-4F90-B7FB-51E7BCF451B6 Q24540329-F3B9279F-9AB5-4A27-A58F-F60DD1C8C9E3 Q24616347-7C5AF213-0AAC-4BD5-B433-D546BE389491 Q24682746-598A52A0-9B69-4447-8473-A469CF59DBEA Q26738910-40F5ECB0-B8D0-4C7D-A739-B68DF806AB7E Q26824051-E1641127-E3AC-489F-B018-015036254C45 Q26825224-7063B9B5-5885-43BD-9CBA-A35050AE4F37 Q27025814-81DFC515-C451-426C-AC69-26CAA75CD47B Q27301070-97723E04-659D-4099-9343-AFF0FB97DA3F Q28081905-4BF29F42-B6D6-4E00-B963-4C4855012F71 Q28299474-F1251877-99B0-4A94-B92A-3259D09476EC Q28392635-1726C400-802A-4BF5-812E-3900E74F7976 Q28468302-5ADBE07B-1521-4A9F-B0AA-F5AECE72FB54 Q28507204-FF0C1749-DBA4-4E75-B0E7-BDEA0AD1FCF4 Q28508871-EFFD9B9E-D8C5-4B9F-8902-ADC196C0DB53 Q28582251-E3691899-82F9-403E-A2EA-EA6B8074A309 Q28587278-23C8CA0B-C684-46BD-B0C9-E93CC81B8B37 Q28591439-68CEE52A-6922-4B5D-8B05-E55F8813A2A0 Q30581713-BD97730F-5FD9-49EA-91FE-F4157331334B Q33305119-5E114A3B-B691-4268-B5AA-68EAEB849E5A Q33570384-8C17C039-8B37-4DD4-B796-0AAEBBC9EEE6 Q33650497-424E900A-2B4F-4AE7-B72A-9ED1CCC1AF6D Q33666278-4D60A1B3-3FB3-4B6E-B7D5-E76157E819D6 Q33705386-B2BF65C5-466D-408A-829F-F8C77265E636 Q33726825-D3C784D9-7596-4551-BCBC-0EC8BE219278 Q33788461-8CC91995-A02F-4A00-9994-CA6B4E0979D6 Q33801655-6F9B3735-396D-4728-9627-588432C143D3 Q33922520-BB7426A7-2B78-4054-ABDF-23EEA036DCBA Q33935986-7C04A60D-D8AC-4220-8521-9C90838142B4 Q34063783-B33D0878-9BD6-4017-9480-FE2D44B7B81D Q34071914-B53736A5-B578-435A-BF22-A703D79DE5C0 Q34083706-E5049FBB-6288-4741-8C70-22A1EF428B0D Q34116923-2B079C40-0912-4EC9-9153-A7183111BF4A Q34193048-18E9D0E3-4153-4A7F-88DC-ADD832EC2992 Q34346949-9DD9656B-0439-46E0-BF38-9A28B976ED3F Q34479857-7E343736-B022-474D-ADF5-C92A54E2B507 Q34567677-31442E70-659A-4723-867E-1FE7E7365AF2 Q34577826-3CA183F9-9C36-4BFF-A066-7CD1DBE53FBC Q34703974-0AEC29BE-F0BE-48A4-8E79-B1C65F84375A

P2860

[Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier

http://www.wikidata.org/entity/Q24652657

description

2002 nî lūn-bûn

@nan

2002 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

[Beta]IV-spectrin regulates so ...... segments and nodes of Ranvier

@ast

[Beta]IV-spectrin regulates so ...... segments and nodes of Ranvier

@en

[Beta]IV-spectrin regulates so ...... segments and nodes of Ranvier

@nl

type

label

[Beta]IV-spectrin regulates so ...... segments and nodes of Ranvier

@ast

[Beta]IV-spectrin regulates so ...... segments and nodes of Ranvier

@en

[Beta]IV-spectrin regulates so ...... segments and nodes of Ranvier

@nl

prefLabel

[Beta]IV-spectrin regulates so ...... segments and nodes of Ranvier

@ast

[Beta]IV-spectrin regulates so ...... segments and nodes of Ranvier

@en

[Beta]IV-spectrin regulates so ...... segments and nodes of Ranvier

@nl

P1433

Q24652657-1AB92F8D-8F6D-482B-AED9-8FA3961D7DBA

P1476

Q24652657-A1F8953A-E635-46AA-8FC4-2D44C43FEC02

P2093

Q24652657-1479FBE2-080A-449C-8DE1-53568E738EF4

P2860

Q24652657-082909CE-1756-4F5A-9D87-15BF0403D35C

Q24652657-0A18B6C4-118F-49A7-A953-AA2AFAA5C222

Q24652657-1090AAAB-3DEE-4A18-888C-FA034BF36FF7

Q24652657-145A7EAB-8C3D-4946-8DED-CBD54466FC7D

Q24652657-153EA162-3DE2-40D5-8C6E-EC4BFF6E0337

Q24652657-1C62652B-1320-425C-8C0E-43F80A8F18AC

Q24652657-1DA65363-2CB5-4810-94BB-501203CAB91D

Q24652657-2104C52E-2F52-4B6D-BC8A-B2CE3F2E7149

Q24652657-3A5C9A0E-9505-49D5-A525-FA61CBE97DB4

Q24652657-3FD05EFE-8AC7-48A0-B605-5772C13EF83A

P304

Q24652657-332EDF83-F1B4-4741-90DE-A7A9C3EDDD3A

P31

Q24652657-1891E04A-5D3D-41F0-888B-6F7B70D7650D

P3181

Q24652657-5F6AAFC3-FCB5-4B8F-AC8D-994990CBB32C

P356

Q24652657-4BFA3CC6-FAD9-4B90-A1F0-2ECC9C82F550

P407

Q24652657-9ADC3B95-6737-4166-A3A2-8F701A0D7C36

P433

Q24652657-30C8E489-D39E-4FF8-8391-A7B153711931

P478

Q24652657-04D62639-E5AD-4283-A2C9-7E9CFB16799E

P50

Q24652657-F51364AB-3275-4480-AE44-8DFB28368F2D

P577

Q24652657-78D58CA5-F940-4213-B8C8-CD769CC0C9A0

P5875

Q24652657-BE28CBDA-21AA-4C96-8FA5-AC59D70F5DBE

P698

Q24652657-57B6144D-16C6-4D08-8696-EBCB6FEEAA5C

P921

Q24652657-763F10B3-E960-490A-91A0-772891F69B2B

P932

Q24652657-C1178149-9911-43F8-BD9B-54914AB0C0D6

P3181

P356

P1433

Journal of Cell Biology

P1476

[Beta]IV-spectrin regulates so ...... segments and nodes of Ranvier

@en

P2093

Masayuki Komada

http://www.w3.org/2001/XMLSchema#string

P2860

Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels

betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system

A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix

AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier

Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses

Targeted ablation of NrCAM or ankyrin-B results in disorganized lens fibers leading to cataract formation

AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing

Spectrin tethers and mesh in the biosynthetic pathway

Ankyrin binds to the 15th repetitive unit of erythroid and nonerythroid beta-spectrin

Mapping the binding sites of human erythrocyte ankyrin for the anion exchanger and spectrin

P304

337-348

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

402948

http://www.w3.org/2001/XMLSchema#string

P356

10.1083/JCB.200110003

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

156

http://www.w3.org/2001/XMLSchema#string

P50

Philippe Soriano

P577

2002-01-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11552319

http://www.w3.org/2001/XMLSchema#string

P698

11807096

http://www.w3.org/2001/XMLSchema#string

P921

P932

2199236

http://www.w3.org/2001/XMLSchema#string