A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
about
Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sitesSpectrin-based skeleton as an actor in cell signalingCounteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein PhosphatasesThe role of late I Na in development of cardiac arrhythmiasChannelopathies from mutations in the cardiac sodium channel protein complexProtein assemblies of sodium and inward rectifier potassium channels control cardiac excitability and arrhythmogenesisCaMKII-dependent regulation of cardiac Na(+) homeostasisCalmodulin-dependent protein kinase II: linking heart failure and arrhythmiasNa+ channel function, regulation, structure, trafficking and sequestrationMechanisms of altered Ca²⁺ handling in heart failureNew therapeutic targets in cardiology: arrhythmias and Ca2+/calmodulin-dependent kinase II (CaMKII)Axon initial segments: diverse and dynamic neuronal compartmentsRole of sodium and calcium dysregulation in tachyarrhythmias in sudden cardiac death.Interactions between ankyrin-G, Plakophilin-2, and Connexin43 at the cardiac intercalated discSodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmiasIκBα is not required for axon initial segment assemblyIntegrative biological analysis for neuropsychopharmacologyAge-related intraneuronal elevation of αII-spectrin breakdown product SBDP120 in rodent forebrain accelerates in 3×Tg-AD miceSimulation and mechanistic investigation of the arrhythmogenic role of the late sodium current in human heart failureDNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease.Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function In Vivo.Cardiac Na Channels: Structure to FunctionAxonal Membranes and Their Domains: Assembly and Function of the Axon Initial Segment and Node of Ranvier.Mild Traumatic Brain Injury Evokes Pyramidal Neuron Axon Initial Segment Plasticity and Diffuse Presynaptic Inhibitory Terminal Loss.Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia.EHD3-dependent endosome pathway regulates cardiac membrane excitability and physiology.Obscure functions: the location-function relationship of obscurins.Tubulin polymerization disrupts cardiac β-adrenergic regulation of late INa.Role of the axonal initial segment in psychiatric disorders: function, dysfunction, and interventionDeletion of FoxO1 leads to shortening of QRS by increasing Na(+) channel activity through enhanced expression of both cardiac NaV1.5 and β3 subunitLocation, location, regulation: a novel role for β-spectrin in the heart.Ankyrin-B protein in heart failure: identification of a new component of metazoan cardioprotection.CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome.Ankyrin-G coordinates intercalated disc signaling platform to regulate cardiac excitability in vivoDiseases caused by mutations in Nav1.5 interacting proteinsNovel aspects of excitation-contraction coupling in heart failure.L-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexinsSchwann cell spectrins modulate peripheral nerve myelination.Ankyrin-G participates in INa remodeling in myocytes from the border zones of infarcted canine heart.
P2860
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P2860
A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
description
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im Oktober 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/10/01)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/10/01)
@nl
наукова стаття, опублікована в жовтні 2010
@uk
مقالة علمية (نشرت في أكتوبر 2010)
@ar
name
A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
@ast
A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
@en
A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
@nl
type
label
A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
@ast
A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
@en
A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
@nl
prefLabel
A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
@ast
A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
@en
A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
@nl
P2093
P2860
P921
P3181
P356
P1476
A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
@en
P2093
Crystal F. Kline
Hjalti Gudmundsson
Jedidiah S. Snyder
Jingdong Li
Mark E. Anderson
Matthew N. Rasband
Natalia Cardona
Nathan P. Davidson
Olha M. Koval
P2860
P304
P3181
P356
10.1172/JCI43621
P407
P577
2010-10-01T00:00:00Z