betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system
about
A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrixSpectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissuesIslet cell autoantigen of 69 kDa is an arfaptin-related protein associated with the Golgi complex of insulinoma INS-1 cellsLateral membrane biogenesis in human bronchial epithelial cells requires 190-kDa ankyrin-GTyrosine phosphorylation regulates alpha II spectrin cleavage by calpainWhere is the spike generator of the cochlear nerve? Voltage-gated sodium channels in the mouse cochlea.Dephosphorylation of beta2-syntrophin and Ca2+/mu-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretionSpectrin-based skeleton as an actor in cell signaling[Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of RanvierDisrupted axo-glial junctions result in accumulation of abnormal mitochondria at nodes of ranvierAnkyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segmentsSyndecan-3 and syndecan-4 are enriched in Schwann cell perinodal processesAxon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron PolarityMultimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activityThe prototypical 4.1R-10-kDa domain and the 4.1g-10-kDa paralog mediate fodrin-actin complex formationc-Src binds alpha II spectrin's Src homology 3 (SH3) domain and blocks calpain susceptibility by phosphorylating Tyr1176Integrative biological analysis for neuropsychopharmacologyADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axonsTargeted deletion of betaIII spectrin impairs synaptogenesis and generates ataxic and seizure phenotypes.A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of RanvierMultiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axonsSpecific role of the truncated betaIV-spectrin Sigma6 in sodium channel clustering at axon initial segments and nodes of ranvierNodes of Ranvier and axon initial segments are ankyrin G-dependent domains that assemble by distinct mechanismsA β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in miceBetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segmentsElectrical excitability of early neurons in the human cerebral cortex during the second trimester of gestation.In vivo assembly of the axon initial segment in motor neuronsSerotonin modulates spike probability in the axon initial segment through HCN channels.Accumulation of phosphorylated I kappaB alpha and activated IKK in nodes of Ranvier.Disruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury.Sorting of Dendritic and Axonal Vesicles at the Pre-axonal Exclusion Zone.Axonal Membranes and Their Domains: Assembly and Function of the Axon Initial Segment and Node of Ranvier.Myelination and regional domain differentiation of the axon.Organization and maintenance of molecular domains in myelinated axonsThe dense core transmembrane vesicle protein IA-2 is a regulator of vesicle number and insulin secretion.Developing nodes of Ranvier are defined by ankyrin-G clustering and are independent of paranodal axoglial adhesion.Microwave & magnetic (M2) proteomics reveals CNS-specific protein expression waves that precede clinical symptoms of experimental autoimmune encephalomyelitis.Axon physiology.Ankyrin G restricts ion channel diffusion at the axonal initial segment before the establishment of the diffusion barrierOligodendrocyte myelin glycoprotein does not influence node of ranvier structure or assembly.
P2860
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P248
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P2860
betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
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2000年論文
@zh-mo
2000年論文
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2000年论文
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name
betaIV spectrin, a new spectri ...... and peripheral nervous system
@ast
betaIV spectrin, a new spectri ...... and peripheral nervous system
@en
betaIV spectrin, a new spectri ...... and peripheral nervous system
@en-gb
betaIV spectrin, a new spectri ...... and peripheral nervous system
@nl
type
label
betaIV spectrin, a new spectri ...... and peripheral nervous system
@ast
betaIV spectrin, a new spectri ...... and peripheral nervous system
@en
betaIV spectrin, a new spectri ...... and peripheral nervous system
@en-gb
betaIV spectrin, a new spectri ...... and peripheral nervous system
@nl
prefLabel
betaIV spectrin, a new spectri ...... and peripheral nervous system
@ast
betaIV spectrin, a new spectri ...... and peripheral nervous system
@en
betaIV spectrin, a new spectri ...... and peripheral nervous system
@en-gb
betaIV spectrin, a new spectri ...... and peripheral nervous system
@nl
P2093
P2860
P921
P3181
P356
P1476
betaIV spectrin, a new spectri ...... and peripheral nervous system
@en
P2093
D Aggujaro
E Maksimova
M Solimena
W Philbrick
P2860
P304
P3181
P356
10.1083/JCB.151.5.985
P407
P577
2000-11-01T00:00:00Z