Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
about
The nuclear envelopathies and human diseasesReverse engineering of the spindle assembly checkpointHuman BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APCImpairment of MAD2B-PRCC interaction in mitotic checkpoint defective t(X;1)-positive renal cell carcinomasCrystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpointCrystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinaseMad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochoresLesions in many different spindle components activate the spindle checkpoint in the budding yeast Saccharomyces cerevisiaeThe checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiationHuman enhancer of invasion-cluster, a coiled-coil protein required for passage through mitosisMAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activityCheckpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activityMad2 transiently associates with an APC/p55Cdc complex during mitosisSpindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochoresMammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complexThe current view for the silencing of the spindle assembly checkpointCdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae.Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways.Bub1 kinase targets Sgo1 to ensure efficient chromosome biorientation in budding yeast mitosis.Ypi1, a positive regulator of nuclear protein phosphatase type 1 activity in Saccharomyces cerevisiae.The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins.Distinct chromosome segregation roles for spindle checkpoint proteins.Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2Cdk1 promotes kinetochore bi-orientation and regulates Cdc20 expression during recovery from spindle checkpoint arrestA novel yeast screen for mitotic arrest mutants identifies DOC1, a new gene involved in cyclin proteolysis.Novel sfi1 alleles uncover additional functions for Sfi1p in bipolar spindle assembly and function.Bifurcation of the mitotic checkpoint pathway in budding yeast.MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p.Ctf19p: A novel kinetochore protein in Saccharomyces cerevisiae and a potential link between the kinetochore and mitotic spindle.Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae.The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeastThe yeast protein kinase Mps1p is required for assembly of the integral spindle pole body component Spc42p.Ipl1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores.The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpointCdk phosphorylation of a nucleoporin controls localization of active genes through the cell cycle.The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint.
P2860
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P2860
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
description
1995 nî lūn-bûn
@nan
1995 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
@ast
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
@en
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
@nl
type
label
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
@ast
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
@en
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
@nl
prefLabel
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
@ast
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
@en
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
@nl
P2860
P356
P1476
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
@en
P2093
A W Murray
P2860
P304
P356
10.1083/JCB.131.3.709
P407
P577
1995-11-01T00:00:00Z