Mad2 transiently associates with an APC/p55Cdc complex during mitosis
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Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complexEvidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2betaCrystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpointShugoshin is a Mad1/Cdc20-like interactor of Mad2Determinants of conformational dimerization of Mad2 and its inhibition by p31cometIdentification of a MAD2-binding protein, CMT2, and its role in mitosis.Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochoresHaploinsufficiency of the Mus81-Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cellsCheckpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complexIdentification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulationConformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpointCdc20 associates with the kinase aurora2/AikCheckpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2Nuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylationThe anaphase promoting complex/cyclosome: a machine designed to destroyKinetochore "memory" of spindle checkpoint signaling in lysed mitotic cells.The maize homologue of the cell cycle checkpoint protein MAD2 reveals kinetochore substructure and contrasting mitotic and meiotic localization patterns.Phosphorylation of the mitotic regulator Pds1/securin by Cdc28 is required for efficient nuclear localization of Esp1/separaseStructure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex.Control of mitotic transitions by the anaphase-promoting complex.Components of the spindle-assembly checkpoint are essential in Caenorhabditis elegans.Mitotic chromosomal instability and cancer: mouse modelling of the human disease.The spindle checkpoint, aneuploidy, and cancer.Role of cyclin B1/Cdc2 up-regulation in the development of mitotic prometaphase arrest in human breast cancer cells treated with nocodazoleMad2 phosphorylation regulates its association with Mad1 and the APC/C.The spindle checkpoint: structural insights into dynamic signalling.Mitotic checkpoints, genetic instability, and cancer.Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymeraseMouse oocytes depend on BubR1 for proper chromosome segregation but not for prophase I arrestRunning on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint.Anaphase-promoting complex-dependent proteolysis of cell cycle regulators and genomic instability of cancer cells.Elevated level of spindle checkprotein MAD2 correlates with cellular mitotic arrest, but not with aneuploidy and clinicopathological characteristics in gastric cancer.Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation.Rev7/Mad2B plays a critical role in the assembly of a functional mitotic spindle.Requirements for protein phosphorylation and the kinase activity of polo-like kinase 1 (Plk1) for the kinetochore function of mitotic arrest deficiency protein 1 (Mad1).A quantitative systems view of the spindle assembly checkpoint.Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells.How oocytes try to get it right: spindle checkpoint control in meiosis.
P2860
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P2860
Mad2 transiently associates with an APC/p55Cdc complex during mitosis
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Mad2 transiently associates with an APC/p55Cdc complex during mitosis
@ast
Mad2 transiently associates with an APC/p55Cdc complex during mitosis
@en
Mad2 transiently associates with an APC/p55Cdc complex during mitosis
@nl
type
label
Mad2 transiently associates with an APC/p55Cdc complex during mitosis
@ast
Mad2 transiently associates with an APC/p55Cdc complex during mitosis
@en
Mad2 transiently associates with an APC/p55Cdc complex during mitosis
@nl
prefLabel
Mad2 transiently associates with an APC/p55Cdc complex during mitosis
@ast
Mad2 transiently associates with an APC/p55Cdc complex during mitosis
@en
Mad2 transiently associates with an APC/p55Cdc complex during mitosis
@nl
P2860
P356
P1476
Mad2 transiently associates with an APC/p55Cdc complex during mitosis
@en
P2093
P2860
P304
P356
10.1073/PNAS.95.19.11193
P407
P577
1998-09-15T00:00:00Z