Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor - Wikidata - wikimedia - TriplyDB

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

http://www.wikidata.org/entity/Q24305821

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Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor A novel proteomic screen for peptide-protein interactions Carcinogenesis and translational controls: TACC1 is down-regulated in human cancers and associates with mRNA regulators Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain The phosphotyrosine interaction domain of Shc binds an LXNPXY motif on the epidermal growth factor receptor Structural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motif Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein Rapid identification of phosphopeptide ligands for SH2 domains. Screening of peptide libraries by fluorescence-activated bead sorting The Grb2-mSos1 complex binds phosphopeptides with higher affinity than Grb2 Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase.Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation N terminus of Sos1 Ras exchange factor: critical roles for the Dbl and pleckstrin homology domains Recruitment of the class II phosphoinositide 3-kinase C2beta to the epidermal growth factor receptor: role of Grb2 Identification of a new Pyk2 target protein with Arf-GAP activity A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways Tyrosine phosphorylation sites at amino acids 239 and 240 of Shc are involved in epidermal growth factor-induced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activation A comprehensive pathway map of epidermal growth factor receptor signaling Fully automated synthesis of (phospho)peptide arrays in microtiter plate wells provides efficient access to protein tyrosine kinase characterization The docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathway Current Understanding on EGFR and Wnt/β-Catenin Signaling in Glioma and Their Possible Crosstalk EGF receptor trafficking: consequences for signaling and cancer Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode Metastasis-associated PRL-3 induces EGFR activation and addiction in cancer cells Direct binding of the signaling adapter protein Grb2 to the activation loop tyrosines on the nerve growth factor receptor tyrosine kinase, TrkA PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules Mutation of a Shc binding site tyrosine residue in ErbB3/HER3 blocks heregulin-dependent activation of mitogen-activated protein kinase Phosphotyrosine 1173 mediates binding of the protein-tyrosine phosphatase SHP-1 to the epidermal growth factor receptor and attenuation of receptor signaling B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins ShcA tyrosine phosphorylation sites can replace ShcA binding in signalling by middle T-antigen Quantification and kinetic analysis of Grb2-EGFR interaction on micro-patterned surfaces for the characterization of EGFR-modulating substances Modeling Cellular Noise Underlying Heterogeneous Cell Responses in the Epidermal Growth Factor Signaling Pathway Nerve growth factor stimulates the tyrosine phosphorylation of endogenous Crk-II and augments its association with p130Cas in PC-12 cells

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Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

http://www.wikidata.org/entity/Q24305821

description

1994 nî lūn-bûn

@nan

1994 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1994 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

1994年の論文

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1994年論文

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1994年論文

@zh-hant

1994年論文

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1994年論文

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1994年論文

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1994年论文

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name

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

@ast

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

@en

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

@en-gb

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

@nl

type

label

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

@ast

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

@en

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

@en-gb

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

@nl

prefLabel

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

@ast

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

@en

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

@en-gb

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

@nl

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Molecular and Cellular Biology

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Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

@en

P2093

A G Batzer

http://www.w3.org/2001/XMLSchema#string

D Rotin

http://www.w3.org/2001/XMLSchema#string

E Y Skolnik

http://www.w3.org/2001/XMLSchema#string

J M Ureña

http://www.w3.org/2001/XMLSchema#string

J Schlessinger

http://www.w3.org/2001/XMLSchema#string

P2860

GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit

Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation

Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma

Binding of GAP to activated PDGF receptors

Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases

The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp

A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1

Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor

The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-gamma

In vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinase

P304

5192-201

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scholarly article

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4429476

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10.1128/MCB.14.8.5192

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P433

8

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P478

14

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P577

1994-08-01T00:00:00Z

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7518560

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359038

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