Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1 - Wikidata - wikimedia - TriplyDB

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

http://www.wikidata.org/entity/Q24679555

about

Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes.Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.PGC-1 coactivators: inducible regulators of energy metabolism in health and disease Mitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exercise Genes and pathophysiology of type 2 diabetes: more than just the Randle cycle all over again Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction mTOR signaling in growth control and disease Major urinary protein-1 increases energy expenditure and improves glucose intolerance through enhancing mitochondrial function in skeletal muscle of diabetic mice Antioxidants prevent health-promoting effects of physical exercise in humans Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion Epigenetics: a molecular link between environmental factors and type 2 diabetes Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells SCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity Linking disease-associated genes to regulatory networks via promoter organization New methods for finding disease-susceptibility genes: impact and potential Genetics and functional genomics of type 2 diabetes mellitus PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents Mitochondrial Quality Control and Muscle Mass Maintenance Complex Coordination of Cell Plasticity by a PGC-1α-controlled Transcriptional Network in Skeletal Muscle The Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for Treatment Developmental perturbation induced by maternal asthma during pregnancy: the short- and long-term impacts on offspring Epigenetics: the missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetes Redox regulation of mitochondrial biogenesis Implications of mitochondrial uncoupling in skeletal muscle in the development and treatment of obesity Parkinson's disease, insulin resistance and novel agents of neuroprotection New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond Role of lipotoxicity in endothelial dysfunction Acylcarnitines: reflecting or inflicting insulin resistance?Exercise as an intervention to improve metabolic outcomes after intrauterine growth restriction Rosiglitazone-induced mitochondrial biogenesis in white adipose tissue is independent of peroxisome proliferator-activated receptor γ coactivator-1α

P2860

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P2860

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

http://www.wikidata.org/entity/Q24679555

description

2003 nî lūn-bûn

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2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2003 թվականի հուլիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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Coordinated reduction of genes ...... otential role of PGC1 and NRF1

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Coordinated reduction of genes ...... otential role of PGC1 and NRF1

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Coordinated reduction of genes ...... otential role of PGC1 and NRF1

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Coordinated reduction of genes ...... otential role of PGC1 and NRF1

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Coordinated reduction of genes ...... otential role of PGC1 and NRF1

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Coordinated reduction of genes ...... otential role of PGC1 and NRF1

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Coordinated reduction of genes ...... otential role of PGC1 and NRF1

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Coordinated reduction of genes ...... otential role of PGC1 and NRF1

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Coordinated reduction of genes ...... otential role of PGC1 and NRF1

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Proceedings of the National Academy of Sciences of the United States of America

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Coordinated reduction of genes ...... otential role of PGC1 and NRF1

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Allison B Goldfine

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Edward Mun

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Edwin J Landaker

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Jean Finlayson

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Kenneth Cusi

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Lawrence J Mandarino

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Mary Elizabeth Patti

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Maura Costello

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Rachele Berria

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Robert Saccone

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P2860

Insulin signalling and the regulation of glucose and lipid metabolism

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation.

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

Cluster analysis and display of genome-wide expression patterns

MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data

Cloning and mRNA tissue distribution of human PPARgamma coactivator-1.

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes

Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

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8466-71

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14

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100

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Ralph A DeFronzo

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2003-07-08T00:00:00Z

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10684983

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12832613

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