Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication
about
Structural basis for DNA binding by replication initiator Mcm10Physical Interactions between Mcm10, DNA, and DNA PolymeraseSolution NMR Structure of the C-terminal DNA Binding Domain of Mcm10 Reveals a Conserved MCM MotifMcm10 Self-Association Is Mediated by an N-Terminal Coiled-Coil DomainMcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation.A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome.An Mcm10 Mutant Defective in ssDNA Binding Shows Defects in DNA Replication InitiationDrosophila Mcm10 is required for DNA replication and differentiation in the compound eyeA DNA polymerase-{alpha}{middle dot}primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cellsRecQL4 is required for the association of Mcm10 and Ctf4 with replication origins in human cellsXenopus DNA2 is a helicase/nuclease that is found in complexes with replication proteins And-1/Ctf4 and Mcm10 and DSB response proteins Nbs1 and ATMCloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the central zinc-binding domain of the human Mcm10 DNA-replication factorNovel roles of HP1a and Mcm10 in DNA replication, genome maintenance and photoreceptor cell differentiation.Ultraviolet radiation stress triggers the down-regulation of essential replication factor Mcm10.The N-terminus of Mcm10 is important for interaction with the 9-1-1 clamp and in resistance to DNA damage.Characterization of Leishmania donovani MCM4: expression patterns and interaction with PCNA.Multiple functions for Drosophila Mcm10 suggested through analysis of two Mcm10 mutant allelesUbc4 and Not4 regulate steady-state levels of DNA polymerase-α to promote efficient and accurate DNA replication.Evolution of CST function in telomere maintenance.Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG componentsArchaeology of eukaryotic DNA replicationReduced expression of GINS complex members induces hallmarks of pre-malignancy in primary untransformed human cellsA transcriptome-based model of central memory CD4 T cell death in HIV infection.Emerging players in the initiation of eukaryotic DNA replication.miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancerAssembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins.Nuclear export factor RBM15 facilitates the access of DBP5 to mRNAStructural biology of replication initiation factor Mcm10.Enigmatic roles of Mcm10 in DNA replicationMCM10: one tool for all-Integrity, maintenance and damage control.Relationships between deficits in tissue mass and transcriptional programs after partial hepatectomy in miceAtaxia telangiectasia-mutated damage-signaling kinase- and proteasome-dependent destruction of Mre11-Rad50-Nbs1 subunits in Simian virus 40-infected primate cellsOverexpression of minichromosome maintenance protein 10 in medulloblastoma and its clinical implications.Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation.Mcm10: A Dynamic Scaffold at Eukaryotic Replication ForksSlx5/Slx8 Promotes Replication Stress Tolerance by Facilitating Mitotic ProgressionHuman Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in.Xenopus Mcm10 is a CDK-substrate required for replication fork stability.Discovery of gene expression-based pharmacodynamic biomarker for a p53 context-specific anti-tumor drug Wee1 inhibitor.DNA-Directed Polymerase Subunits Play a Vital Role in Human Telomeric Overhang Processing.
P2860
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P2860
Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Human Mcm10 regulates the cata ...... DNA damage during replication
@ast
Human Mcm10 regulates the cata ...... DNA damage during replication
@en
Human Mcm10 regulates the cata ...... DNA damage during replication
@nl
type
label
Human Mcm10 regulates the cata ...... DNA damage during replication
@ast
Human Mcm10 regulates the cata ...... DNA damage during replication
@en
Human Mcm10 regulates the cata ...... DNA damage during replication
@nl
prefLabel
Human Mcm10 regulates the cata ...... DNA damage during replication
@ast
Human Mcm10 regulates the cata ...... DNA damage during replication
@en
Human Mcm10 regulates the cata ...... DNA damage during replication
@nl
P2860
P3181
P356
P1476
Human Mcm10 regulates the cata ...... DNA damage during replication
@en
P2093
Anja-Katrin Bielinsky
Sharbani Chattopadhyay
P2860
P304
P3181
P356
10.1091/MBC.E06-12-1148
P407
P577
2007-10-01T00:00:00Z