A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice - Wikidata - wikimedia - TriplyDB

A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice

A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice

http://www.wikidata.org/entity/Q24685118

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Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis Sulfated glycosaminoglycans are required for specific and sensitive fibroblast growth factor (FGF) 19 signaling via FGF receptor 4 and betaKlotho Liver-specific activities of FGF19 require Klotho beta FGF-21 as a novel metabolic regulator.Endocrine fibroblast growth factors 15/19 and 21: from feast to famine Recent advances in understanding and managing cholestasis Novel bile acid therapeutics for the treatment of chronic liver diseases Fibroblast Growth Factor Signaling in Metabolic Regulation FXR signaling in the enterohepatic system New insights in hepatocellular carcinoma: from bench to bedside Fibroblast growth factors in cardiovascular disease: The emerging role of FGF21 Prevention of hepatocellular carcinoma: potential targets, experimental models, and clinical challenges Fundamentals of FGF19 & FGF21 action in vitro and in vivo Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models Characterization of a FGF19 variant with altered receptor specificity revealed a central role for FGFR1c in the regulation of glucose metabolism FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways The Role and Potential Therapeutic Implications of the Fibroblast Growth Factors in Energy Balance and Type 2 Diabetes.Therapeutic utilities of fibroblast growth factor 19.High-level expression and purification of soluble recombinant FGF21 protein by SUMO fusion in Escherichia coli.Fibroblast growth factor 15 deficiency impairs liver regeneration in mice.FGF19-induced hepatocyte proliferation is mediated through FGFR4 activation.Non-cell-autonomous activation of IL-6/STAT3 signaling mediates FGF19-driven hepatocarcinogenesis.Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?Enhanced in vitro refolding of fibroblast growth factor 15 with the assistance of SUMO fusion partner Separating mitogenic and metabolic activities of fibroblast growth factor 19 (FGF19).Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma Serum FGF-21 levels in type 2 diabetic patients.Expression of fibroblast growth factor 19 is associated with recurrence and poor prognosis of hepatocellular carcinoma.Experimental models of hepatocellular carcinoma Fibroblast growth factors: biology, function, and application for tissue regeneration.Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screening FGFR4 role in epithelial-mesenchymal transition and its therapeutic value in colorectal cancer Upregulated expression of a unique gene by hepatitis B x antigen promotes hepatocellular growth and tumorigenesis.Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21.Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling.Bile Acids as Hormones: The FXR-FGF15/19 Pathway Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis.The Wnt/β-catenin signaling pathway in liver biology and disease.Loss of FGF21 in diabetic mouse during hepatocellular carcinogenetic transformation Expression of hepatic Fibroblast Growth Factor 19 is enhanced in Primary Biliary Cirrhosis and correlates with severity of the disease

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A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice

http://www.wikidata.org/entity/Q24685118

description

2002 nî lūn-bûn

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2002 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2002 թվականի հունիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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A mouse model of hepatocellula ...... etal muscle of transgenic mice

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A mouse model of hepatocellula ...... etal muscle of transgenic mice

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A mouse model of hepatocellula ...... etal muscle of transgenic mice

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A mouse model of hepatocellula ...... etal muscle of transgenic mice

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A mouse model of hepatocellula ...... etal muscle of transgenic mice

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A mouse model of hepatocellula ...... etal muscle of transgenic mice

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A mouse model of hepatocellula ...... etal muscle of transgenic mice

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A mouse model of hepatocellula ...... etal muscle of transgenic mice

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The American Journal of Pathology

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A mouse model of hepatocellula ...... etal muscle of transgenic mice

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Barbara Wright

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Dorothy M French

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Elizabeth Tomlinson

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Gretchen D Frantz

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Jean-Philippe Stephan

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Jeremy Stinson

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Katrina Nicholes

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Kenneth Hillan

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Lisa Dillard-Telm

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Siao Ping Tsai

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P2860

FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

Fibroblast growth factors

FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family

Specificity for fibroblast growth factors determined by heparan sulfate in a binary complex with the receptor kinase

Enhanced invasion and tumor growth of fibroblast growth factor 8b-overexpressing MCF-7 human breast cancer cells

FGF-8b increases angiogenic capacity and tumor growth of androgen-regulated S115 breast cancer cells

Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers

Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma

beta-catenin is a target for the ubiquitin-proteasome pathway

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2295-307

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10.1016/S0002-9440(10)61177-7

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1850847

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