Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders
about
Crif1 is a novel transcriptional coactivator of STAT3Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwayCrystal structure of a cytokine-binding region of gp130.Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart functionSelf-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3A Stat3-interacting protein (StIP1) regulates cytokine signal transductiongp130 cytokine signaling in the pituitary gland: a paradigm for cytokine-neuro-endocrine pathwaysTargeted disruption of the mouse Stat3 gene leads to early embryonic lethalityBiology of recently discovered cytokines: discerning the pro- and anti-inflammatory properties of interleukin-27Profiling gene expression in growth-arrested mouse embryos in diapauseLate gestation modulation of fetal glucocorticoid effects requires the receptor for leukemia inhibitory factor: an observational studyTherapeutic strategies for the clinical blockade of IL-6/gp130 signalingDifferential regulation of leukemia inhibitory factor-stimulated neuronal gene expression by protein phosphatases SHP-1 and SHP-2 through mitogen-activated protein kinase-dependent and -independent pathwaysStemness, fusion and renewal of hematopoietic and embryonic stem cellsFetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer.Signals through gp130 upregulate Wnt5a and contribute to cell adhesion in cardiac myocytesAstrocyte differentiation mediated by LIF in cooperation with BMP2Elevated CXCL1 expression in gp130-deficient endothelial cells impairs neutrophil migration in miceHematopoietic stem cell: self-renewal versus differentiationMatters of the heart.The glands have it.Role of cytokine signaling during nervous system developmentReal time analysis of STAT3 nucleocytoplasmic shuttling.Lhx2 expression promotes self-renewal of a distinct multipotential hematopoietic progenitor cell in embryonic stem cell-derived embryoid bodiesExpression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.Specificity of signaling by hematopoietic cytokine receptors: instructive versus permissive effects.CD9 is associated with leukemia inhibitory factor-mediated maintenance of embryonic stem cells.Research resource: interactome of human embryo implantation: identification of gene expression pathways, regulation, and integrated regulatory networks.Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryosNeural activities of IL-6-type cytokines often depend on soluble cytokine receptors.Cardiotrophin-1 (CT-1): a novel hypertrophic and cardioprotective agent.Infarction-induced cytokines cause local depletion of tyrosine hydroxylase in cardiac sympathetic nervesCytokines and their receptors in cardiovascular diseases--role of gp130 signalling pathway in cardiac myocyte growth and maintenance.Receptor recognition by gp130 cytokines.Interleukin 6 and liver regenerationDistinct role of gp130 activation in promoting self-renewal divisions by mitogenically stimulated murine hematopoietic stem cells.Unravelling the pathophysiology of heart failure through human genomics.Neurotrophic factors and gene therapy in spinal cord injury.Biological roles of uterine glands in pregnancy.Uterine glands: biological roles in conceptus implantation, uterine receptivity and decidualization.
P2860
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P2860
Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Targeted disruption of gp130, ...... al and hematological disorders
@ast
Targeted disruption of gp130, ...... al and hematological disorders
@en
Targeted disruption of gp130, ...... al and hematological disorders
@nl
type
label
Targeted disruption of gp130, ...... al and hematological disorders
@ast
Targeted disruption of gp130, ...... al and hematological disorders
@en
Targeted disruption of gp130, ...... al and hematological disorders
@nl
prefLabel
Targeted disruption of gp130, ...... al and hematological disorders
@ast
Targeted disruption of gp130, ...... al and hematological disorders
@en
Targeted disruption of gp130, ...... al and hematological disorders
@nl
P2093
P2860
P356
P1476
Targeted disruption of gp130, ...... al and hematological disorders
@en
P2093
A Kumanogoh
H Fujiwara
S Suematsu
P2860
P304
P356
10.1073/PNAS.93.1.407
P407
P577
1996-01-09T00:00:00Z