Fusion of the NUP98 gene with the LEDGF/p52 gene defines a recurrent acute myeloid leukemia translocation
about
Lens epithelium-derived growth factor deSumoylation by Sumo-specific protease-1 regulates its transcriptional activation of small heat shock protein and the cellular responseVirological and cellular roles of the transcriptional coactivator LEDGF/p75Transcriptional co-activator LEDGF interacts with Cdc7-activator of S-phase kinase (ASK) and stimulates its enzymatic activityA tripartite DNA-binding element, comprised of the nuclear localization signal and two AT-hook motifs, mediates the association of LEDGF/p75 with chromatin in vivoMetallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation.The role of NUP98 gene fusions in hematologic malignancyExpression of the stress response oncoprotein LEDGF/p75 in human cancer: a study of 21 tumor types.Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing.Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins.The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIV.Disruption of Ledgf/Psip1 results in perinatal mortality and homeotic skeletal transformationsNUP98 rearrangements in hematopoietic malignancies: a study of the Groupe Francophone de Cytogénétique Hématologique.Alternative splicing and caspase-mediated cleavage generate antagonistic variants of the stress oncoprotein LEDGF/p75.LEDGF (p75) promotes DNA-end resection and homologous recombination.High-resolution profiling of the LEDGF/p75 chromatin interaction in the ENCODE region.Lens epithelium-derived growth factor/p75 interacts with the transposase-derived DDE domain of PogZ.Evidence for mitochondrial localization of a novel human sialidase (NEU4).Chromatin targeting of de novo DNA methyltransferases by the PWWP domain.LEDGFp52 controls rat retinal ganglion cell neurite growth in culture and regulates specific neuronal growth-associated genes and protein production.Expression of the novel NUP98/PSIP1 fusion transcripts in myelodysplastic syndrome with t(9;11)(p22;p15).Acute myeloid leukemiaNucleoporin Gene Fusions and Hematopoietic Malignancies
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P2860
Fusion of the NUP98 gene with the LEDGF/p52 gene defines a recurrent acute myeloid leukemia translocation
description
2001 nî lūn-bûn
@nan
2001 թուականին հրատարակուած գիտական յօդուած
@hyw
2001 թվականին հրատարակված գիտական հոդված
@hy
2001年の論文
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2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
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2001年論文
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2001年论文
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name
Fusion of the NUP98 gene with ...... myeloid leukemia translocation
@ast
Fusion of the NUP98 gene with ...... myeloid leukemia translocation
@en
Fusion of the NUP98 gene with ...... myeloid leukemia translocation
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type
label
Fusion of the NUP98 gene with ...... myeloid leukemia translocation
@ast
Fusion of the NUP98 gene with ...... myeloid leukemia translocation
@en
Fusion of the NUP98 gene with ...... myeloid leukemia translocation
@nl
prefLabel
Fusion of the NUP98 gene with ...... myeloid leukemia translocation
@ast
Fusion of the NUP98 gene with ...... myeloid leukemia translocation
@en
Fusion of the NUP98 gene with ...... myeloid leukemia translocation
@nl
P2093
P2860
P356
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P1476
Fusion of the NUP98 gene with ...... myeloid leukemia translocation
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P2093
P2860
P2888
P356
10.1186/1471-2156-2-20
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P577
2001-01-01T00:00:00Z
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P6179
1005350169