Lens epithelium-derived growth factor/p75 interacts with the transposase-derived DDE domain of PogZ. - Wikidata - wikimedia - TriplyDB

Lens epithelium-derived growth factor/p75 interacts with the transposase-derived DDE domain of PogZ.

Lens epithelium-derived growth factor/p75 interacts with the transposase-derived DDE domain of PogZ.

http://www.wikidata.org/entity/Q39879606

about

The transcriptional co-activator LEDGF/p75 displays a dynamic scan-and-lock mechanism for chromatin tethering Virological and cellular roles of the transcriptional coactivator LEDGF/p75 Transcriptional co-activator LEDGF interacts with Cdc7-activator of S-phase kinase (ASK) and stimulates its enzymatic activity Impact of Chromatin on HIV Replication Embryonic Lethality Due to Arrested Cardiac Development in Psip1/Hdgfrp2 Double-Deficient Mice Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif LEDGF/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors Nuclear protein LEDGF/p75 recognizes supercoiled DNA by a novel DNA-binding domain LEDGF dominant interference proteins demonstrate prenuclear exposure of HIV-1 integrase and synergize with LEDGF depletion to destroy viral infectivity Specificity of antinuclear autoantibodies recognizing the dense fine speckled nuclear pattern: Preferential targeting of DFS70/LEDGFp75 over its interacting partner MeCP2 Dynamics of the ternary complex formed by c-Myc interactor JPO2, transcriptional co-activator LEDGF/p75, and chromatin.SUMOylation of the lens epithelium-derived growth factor/p75 attenuates its transcriptional activity on the heat shock protein 27 promoter.Molecular mechanisms of retroviral integration site selection.Phage display-directed discovery of LEDGF/p75 binding cyclic peptide inhibitors of HIV replication.Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins.TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication Association of polymorphisms in the LEDGF/p75 gene (PSIP1) with susceptibility to HIV-1 infection and disease progression.LEDGF gene silencing impairs the tumorigenicity of prostate cancer DU145 cells by abating the expression of Hsp27 and activation of the Akt/ERK signaling pathway Towards a Safer, More Randomized Lentiviral Vector Integration Profile Exploring Artificial LEDGF Chimeras.POGZ truncating alleles cause syndromic intellectual disability.Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination.Transient Expression of an LEDGF/p75 Chimera Retargets Lentivector Integration and Functionally Rescues in a Model for X-CGD.Research resource: identification of novel coregulators specific for thyroid hormone receptor-β2.Epigenetic repression of LEDGF during UVB exposure by recruitment of SUV39H1 and HDAC1 to the Sp1-responsive elements within LEDGF promoter CpG island Disruption of POGZ Is Associated with Intellectual Disability and Autism Spectrum Disorders.The Interaction Between Lentiviral Integrase and LEDGF: Structural and Functional Insights The significance of autoantibodies to DFS70/LEDGFp75 in health and disease: integrating basic science with clinical understanding.PSIP1/p75 promotes tumorigenicity in breast cancer cells by promoting the transcription of cell cycle genes.LEDGF (p75) promotes DNA-end resection and homologous recombination.Inhibiting the HIV integration process: past, present, and the future.The stress oncoprotein LEDGF/p75 interacts with the methyl CpG binding protein MeCP2 and influences its transcriptional activity HIV-1 integrase modulates the interaction of the HIV-1 cellular cofactor LEDGF/p75 with chromatin.High-resolution profiling of the LEDGF/p75 chromatin interaction in the ENCODE region.Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.Examining non-LTR retrotransposons in the context of the evolving primate brain.Structure based Virtual Screening toward the discovery of novel inhibitors for impeding the protein-protein interaction between HIV-1 integrase and human lens epithelium-derived growth factor (LEDGF/p75).Lens epithelium-derived growth factor/p75 qualifies as a target for HIV gene therapy in the NSG mouse model.Cellular cofactors of lentiviral integrase: from target validation to drug discovery.HIV-1 integrase inhibition: looking at cofactor interactions.Interactions between Retroviruses and the Host Cell Genome.

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P2860

Lens epithelium-derived growth factor/p75 interacts with the transposase-derived DDE domain of PogZ.

http://www.wikidata.org/entity/Q39879606

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh

2009年學術文章

@zh-hant

name

Lens epithelium-derived growth ...... se-derived DDE domain of PogZ.

@en

Lens epithelium-derived growth ...... se-derived DDE domain of PogZ.

@nl

type

label

Lens epithelium-derived growth ...... se-derived DDE domain of PogZ.

@en

Lens epithelium-derived growth ...... se-derived DDE domain of PogZ.

@nl

prefLabel

Lens epithelium-derived growth ...... se-derived DDE domain of PogZ.

@en

Lens epithelium-derived growth ...... se-derived DDE domain of PogZ.

@nl

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P1433

Journal of Biological Chemistry

P1476

Lens epithelium-derived growth ...... se-derived DDE domain of PogZ.

@en

P2093

Jan De Rijck

http://www.w3.org/2001/XMLSchema#string

Jean-Christophe Rain

http://www.w3.org/2001/XMLSchema#string

Jelle Hendrix

http://www.w3.org/2001/XMLSchema#string

Koen Bartholomeeusen

http://www.w3.org/2001/XMLSchema#string

Richard Benarous

http://www.w3.org/2001/XMLSchema#string

Rik Gijsbers

http://www.w3.org/2001/XMLSchema#string

Stéphane Emiliani

http://www.w3.org/2001/XMLSchema#string

P2860

A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening

LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

Identification of the LEDGF/p75 binding site in HIV-1 integrase

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

Multiple sequence alignment with the Clustal series of programs

Fusion of the NUP98 gene with the LEDGF/p52 gene defines a recurrent acute myeloid leukemia translocation

Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium

P304

11467-11477

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scholarly article

P356

10.1074/JBC.M807781200

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P407

P433

17

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P478

284

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P577

2009-02-25T00:00:00Z

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P698

19244240

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P932

2670152

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