Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype
about
Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice.Carcinogen-specific mutations in preferred Ras-Raf pathway oncogenes directed by strand bias.Hypothesis: Towards the origin of cancer epidemics and pathogenesisROCK1 inhibition promotes the self-renewal of a novel mouse mammary cancer stem cell.Genetic mechanisms in Apc-mediated mammary tumorigenesisGenetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing.Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancersBasal but not luminal mammary epithelial cells require PI3K/mTOR signaling for Ras-driven overgrowth.Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer.Introduction of oncogenes into mammary glands in vivo with an avian retroviral vector initiates and promotes carcinogenesis in mouse models.Compartmentalized Ras proteins transform NIH 3T3 cells with different efficienciesOncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras.Common integration sites for MMTV in viral induced mouse mammary tumors.Mammary cells with active Wnt signaling resist ErbB2-induced tumorigenesisIsoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary tumorigenesisOncogenes come of age.Dormant Wnt-initiated mammary cancer can participate in reconstituting functional mammary glands.Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation.The landscape of somatic chromosomal copy number aberrations in GEM models of prostate carcinoma.Comparison of expression profiles of metastatic versus primary mammary tumors in MMTV-Wnt-1 and MMTV-Neu transgenic mice.Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor PhenotypeIndoleamine 2,3-dioxygenase and tumor-induced toleranceMaternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo.Host indoleamine 2,3-dioxygenase: contribution to systemic acquired tumor tolerance.Developmental Contribution of Wnt-signal-responsive Cells to Mouse Reproductive Tract FormationEstrogen receptor positivity in mammary tumors of Wnt-1 transgenic mice is influenced by collaborating oncogenic mutations.Wnt-1 is dominant over neu in specifying mammary tumor expression profiles.
P2860
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P2860
Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Evolution of somatic mutations ...... nced by the inherited genotype
@ast
Evolution of somatic mutations ...... nced by the inherited genotype
@en
Evolution of somatic mutations ...... nced by the inherited genotype
@nl
type
label
Evolution of somatic mutations ...... nced by the inherited genotype
@ast
Evolution of somatic mutations ...... nced by the inherited genotype
@en
Evolution of somatic mutations ...... nced by the inherited genotype
@nl
prefLabel
Evolution of somatic mutations ...... nced by the inherited genotype
@ast
Evolution of somatic mutations ...... nced by the inherited genotype
@en
Evolution of somatic mutations ...... nced by the inherited genotype
@nl
P2860
P356
P1433
P1476
Evolution of somatic mutations ...... nced by the inherited genotype
@en
P2093
Katrina Podsypanina
P2860
P2888
P356
10.1186/1741-7015-2-24
P407
P577
2004-06-15T00:00:00Z
P5875
P6179
1043633412