Molecular switches at the synapse emerge from receptor and kinase traffic
about
Calcium input frequency, duration and amplitude differentially modulate the relative activation of calcineurin and CaMKIIMathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistabilityERK regulation of phosphodiesterase 4 enhances dopamine-stimulated AMPA receptor membrane insertionSubcellular location of PKA controls striatal plasticity: stochastic simulations in spiny dendritesTransient calcium and dopamine increase PKA activity and DARPP-32 phosphorylationA model of late long-term potentiation simulates aspects of memory maintenanceSTDP in a bistable synapse model based on CaMKII and associated signaling pathwaysA kinetic model of dopamine- and calcium-dependent striatal synaptic plasticityTemporal sensitivity of protein kinase a activation in late-phase long term potentiationMemory switches in chemical reaction spaceThe effects of NR2 subunit-dependent NMDA receptor kinetics on synaptic transmission and CaMKII activationIntegration of biochemical and electrical signaling-multiscale model of the medium spiny neuron of the striatumA new principle for information storage in an enzymatic pathway model.Tag-trigger-consolidation: a model of early and late long-term-potentiation and depressionState based model of long-term potentiation and synaptic tagging and captureSignaling logic of activity-triggered dendritic protein synthesis: an mTOR gate but not a feedback switchExperimental and computational aspects of signaling mechanisms of spike-timing-dependent plasticity.The effect of noise on CaMKII activation in a dendritic spine during LTP inductionModeling glutamatergic synapses: insights into mechanisms regulating synaptic efficacy.Mechanisms of induction and maintenance of spike-timing dependent plasticity in biophysical synapse modelsA role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticityMolecular constraints on synaptic tagging and maintenance of long-term potentiation: a predictive model.A model of the roles of essential kinases in the induction and expression of late long-term potentiation.Trafficking motifs as the basis for two-compartment signaling systems to form multiple stable states.Memory maintenance in synapses with calcium-based plasticity in the presence of background activity.Control of βAR- and N-methyl-D-aspartate (NMDA) Receptor-Dependent cAMP Dynamics in Hippocampal Neurons.Synaptic plasticity in vitro and in silico: insights into an intracellular signaling maze.Modelling the molecular mechanisms of synaptic plasticity using systems biology approachesA propagating ERKII switch forms zones of elevated dendritic activation correlated with plasticityPrediction and validation of a mechanism to control the threshold for inhibitory synaptic plasticity.Modeling signal transduction leading to synaptic plasticity: evaluation and comparison of five models.Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition.The Contribution of Spatial and Temporal Molecular Networks in the Induction of Long-term Memory and Its Underlying Synaptic PlasticityIndia's Computational Biology Growth and Challenges.Modeling maintenance of long-term potentiation in clustered synapses: long-term memory without bistabilityLocal signaling with molecular diffusion as a decoder of Ca2+ signals in synaptic plasticity.Atypical PKCs in memory maintenance: the roles of feedback and redundancyβ-adrenergic signaling broadly contributes to LTP induction.Postsynaptic signal transduction models for long-term potentiation and depression.Calcium messenger heterogeneity: a possible signal for spike timing-dependent plasticity.
P2860
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P2860
Molecular switches at the synapse emerge from receptor and kinase traffic
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Molecular switches at the synapse emerge from receptor and kinase traffic
@ast
Molecular switches at the synapse emerge from receptor and kinase traffic
@en
Molecular switches at the synapse emerge from receptor and kinase traffic
@nl
type
label
Molecular switches at the synapse emerge from receptor and kinase traffic
@ast
Molecular switches at the synapse emerge from receptor and kinase traffic
@en
Molecular switches at the synapse emerge from receptor and kinase traffic
@nl
prefLabel
Molecular switches at the synapse emerge from receptor and kinase traffic
@ast
Molecular switches at the synapse emerge from receptor and kinase traffic
@en
Molecular switches at the synapse emerge from receptor and kinase traffic
@nl
P2860
P3181
P1476
Molecular switches at the synapse emerge from receptor and kinase traffic
@en
P2860
P304
P3181
P356
10.1371/JOURNAL.PCBI.0010020
P407
P577
2005-07-01T00:00:00Z