Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens - Wikidata - wikimedia - TriplyDB

Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens

Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens

http://www.wikidata.org/entity/Q27339599

about

Transposon-based screens for cancer gene discovery in mouse models Applications of DNA integrating elements: Facing the bias bully The utility of transposon mutagenesis for cancer studies in the era of genome editing.Retroviral integrations in gene therapy trials Jdp2 downregulates Trp53 transcription to promote leukaemogenesis in the context of Trp53 heterozygosity Genetic screens using the piggyBac transposon Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data.Bioinformatic clonality analysis of next-generation sequencing-derived viral vector integration sites.Cytoreductive conditioning intensity predicts clonal diversity in ADA-SCID retroviral gene therapy patients.Multiscale representation of genomic signals Gene expression profiling of murine T-cell lymphoblastic lymphoma identifies deregulation of S-phase initiating genes.Vector integration and tumorigenesis.Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach Novel molecular and computational methods improve the accuracy of insertion site analysis in Sleeping Beauty-induced tumors.Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model Analyzing the number of common integration sites of viral vectors--new methods and computer programs.PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.TAPDANCE: an automated tool to identify and annotate transposon insertion CISs and associations between CISs from next generation sequence data.Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy.Detecting recurrent gene mutation in interaction network context using multi-scale graph diffusion.Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors.Cancer gene discovery in mouse and man.BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis.Chromatin landscapes of retroviral and transposon integration profiles Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after gammaretroviral vector gene therapy PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia.Generation of lentivirus-induced dendritic cells under GMP-compliant conditions for adaptive immune reconstitution against cytomegalovirus after stem cell transplantation.Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma New methods for finding common insertion sites and co-occurring common insertion sites in transposon- and virus-based genetic screens.The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression.Retroviral insertions in the VISION database identify molecular pathways in mouse lymphoid leukemia and lymphoma Genome-wide transposon screening and quantitative insertion site sequencing for cancer gene discovery in mice.Identifying transposon insertions and their effects from RNA-sequencing data Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks.A Graph Based Framework to Model Virus Integration Sites.Identifying candidate genes involved in brain tumor formation.Sleeping Beauty mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroups.

P2860

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P2860

Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens

http://www.wikidata.org/entity/Q27339599

description

2006 nî lūn-bûn

@nan

2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

@zh-hk

2006年論文

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2006年論文

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2006年论文

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name

Detecting statistically signif ...... nsertional mutagenesis screens

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Detecting statistically signif ...... nsertional mutagenesis screens

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Detecting statistically signif ...... nsertional mutagenesis screens

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type

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Detecting statistically signif ...... nsertional mutagenesis screens

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Detecting statistically signif ...... nsertional mutagenesis screens

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Detecting statistically signif ...... nsertional mutagenesis screens

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PLOS Computational Biology

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Detecting statistically signif ...... nsertional mutagenesis screens

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Anthony Uren

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Jaap Kool

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Lodewyk Wessels

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Marcel Reinders

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P2860

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis.

Transcription start regions in the human genome are favored targets for MLV integration

STAC: A method for testing the significance of DNA copy number aberrations across multiple array-CGH experiments.

RTCGD: retroviral tagged cancer gene database.

Genetic profile of insertion mutations in mouse leukemias and lymphomas.

Retroviral insertional mutagenesis: tagging cancer pathways.

Hopping around the tumor genome: transposons for cancer gene discovery.

Retroviral insertional mutagenesis: past, present and future.

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scholarly article

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10.1371/JOURNAL.PCBI.0020166

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12

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2

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Jeroen de Ridder

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