PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice. - Wikidata - wikimedia - TriplyDB

PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

http://www.wikidata.org/entity/Q34143674

about

The mouse genetics toolkit: revealing function and mechanism Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling PiggyBac transposon vectors: the tools of the human gene encoding Applications of DNA integrating elements: Facing the bias bully The utility of transposon mutagenesis for cancer studies in the era of genome editing.The Influence of LINE-1 and SINE Retrotransposons on Mammalian Genomes A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention.A genetic screen using the PiggyBac transposon in haploid cells identifies Parp1 as a mediator of olaparib toxicity Genetic screens using the piggyBac transposon Comparative analysis of the recently discovered hAT transposon TcBuster in human cells Application of human haploid cell genetic screening model in identifying the genes required for resistance to environmental toxicants: Chlorpyrifos as a case study Leiomodin-3-deficient mice display nemaline myopathy with fast-myofiber atrophy Genome-scale CRISPR-Cas9 knockout screening in human cells Clonal expansion analysis of transposon insertions by high-throughput sequencing identifies candidate cancer genes in a PiggyBac mutagenesis screen MEF2 is a converging hub for histone deacetylase 4 and phosphatidylinositol 3-kinase/Akt-induced transformation.Exploiting the power of LINE-1 retrotransposon mutagenesis for identification of genes involved in embryonic stem cell differentiation.An optimized, broadly applicable piggyBac transposon induction system Somatic genetics empowers the mouse for modeling and interrogating developmental and disease processes.Novel molecular and computational methods improve the accuracy of insertion site analysis in Sleeping Beauty-induced tumors.Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model piggyBac transposon somatic mutagenesis with an activated reporter and tracker (PB-SMART) for genetic screens in mice.Genetically engineered mouse models of PI3K signaling in breast cancer.Effective gene trapping mediated by Sleeping Beauty transposon.Polygenic in vivo validation of cancer mutations using transposons.CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.A versatile in vivo system for directed dissection of gene expression patterns.Post-integration silencing of piggyBac transposable elements in Aedes aegypti.Next-generation models of human cardiogenesis via genome editing A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells.Chromatin landscapes of retroviral and transposon integration profiles Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase High-throughput functional genomics using CRISPR-Cas9.piggyBac insertional mutagenesis screen identifies a role for nuclear RHOA in human ES cell differentiation A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer.Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants.PiggyBac transposon-mediated gene delivery efficiently generates stable transfectants derived from cultured primary human deciduous tooth dental pulp cells (HDDPCs) and HDDPC-derived iPS cells.Genomic instability and mouse microRNAs.Genome-wide transposon screening and quantitative insertion site sequencing for cancer gene discovery in mice.piggyBac-ing models and new therapeutic strategies.

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PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

http://www.wikidata.org/entity/Q34143674

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

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PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

@en

PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

@nl

type

label

PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

@ast

PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

@en

PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

@nl

prefLabel

PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

@ast

PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

@en

PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

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SCIENCE.1193004

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PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice

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Alexander Strong

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Allan Bradley

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Dong Lu

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Fang Tang Yang

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Kosuke Yusa

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Lena Rad

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Lia S Campos

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Meng Amy Li

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Pentao Liu

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Peter Ellis

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P2860

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

Transposon-mediated genome manipulation in vertebrates

A transposon-based genetic screen in mice identifies genes altered in colorectal cancer

Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens

HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis

Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21

The landscape of somatic copy-number alteration across human cancers.

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells

Two distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic mice

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1104-1107

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10.1126/SCIENCE.1193004

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6007

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330

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George S Vassiliou

Jorge de la Rosa

Juan Cadiñanos

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2010-10-14T00:00:00Z

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20947725

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3719098

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