Novel molecular and computational methods improve the accuracy of insertion site analysis in Sleeping Beauty-induced tumors.
about
The utility of transposon mutagenesis for cancer studies in the era of genome editing.Efficient mapping of transgene integration sites and local structural changes in Cre transgenic mice using targeted locus amplification.Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma.Clonal expansion analysis of transposon insertions by high-throughput sequencing identifies candidate cancer genes in a PiggyBac mutagenesis screenGenome walking by next generation sequencing approachesTransposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse modelTAPDANCE: an automated tool to identify and annotate transposon insertion CISs and associations between CISs from next generation sequence data.Sleeping Beauty mouse models identify candidate genes involved in gliomagenesis.Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesisSequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens.A novel bio-sensor based on DNA strand displacementClonal selection drives genetic divergence of metastatic medulloblastoma.Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinomaA Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with OsteosarcomaGenome-wide transposon screening and quantitative insertion site sequencing for cancer gene discovery in mice.A Hyperactive Transposase Promotes Persistent Gene Transfer of a piggyBac DNA TransposonA Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.Adaptive immunity does not strongly suppress spontaneous tumors in a Sleeping Beauty model of cancer.Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma.A Sleeping Beauty screen reveals NF-kB activation in CLL mouse modelDivergent clonal selection dominates medulloblastoma at recurrenceTransposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression.Cancer gene discovery: exploiting insertional mutagenesis.A recellularized human colon model identifies cancer driver genes.A Hybrid Adenoviral Vector System Achieves Efficient Long-Term Gene Expression in the Liver via piggyBac Transposition.Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis.Sleeping Beauty transposon screen identifies signaling modules that cooperate with STAT5 activation to induce B-cell acute lymphoblastic leukemiaResistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf-/- mouse model.Transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms.SBCDDB: Sleeping Beauty Cancer Driver Database for gene discovery in mouse models of human cancers.Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells.Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma in mice.Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq.A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis.Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene.Molecular profiling of nonalcoholic fatty liver disease-associated hepatocellular carcinoma using SB transposon mutagenesisA Universal Fast Colorimetric Method for DNA Signal Detection with DNA Strand Displacement and Gold Nanoparticles
P2860
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P2860
Novel molecular and computational methods improve the accuracy of insertion site analysis in Sleeping Beauty-induced tumors.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Novel molecular and computatio ...... leeping Beauty-induced tumors.
@ast
Novel molecular and computatio ...... leeping Beauty-induced tumors.
@en
Novel molecular and computatio ...... leeping Beauty-induced tumors.
@nl
type
label
Novel molecular and computatio ...... leeping Beauty-induced tumors.
@ast
Novel molecular and computatio ...... leeping Beauty-induced tumors.
@en
Novel molecular and computatio ...... leeping Beauty-induced tumors.
@nl
prefLabel
Novel molecular and computatio ...... leeping Beauty-induced tumors.
@ast
Novel molecular and computatio ...... leeping Beauty-induced tumors.
@en
Novel molecular and computatio ...... leeping Beauty-induced tumors.
@nl
P2093
P2860
P50
P1433
P1476
Novel molecular and computatio ...... leeping Beauty-induced tumors.
@en
P2093
Benjamin T Brett
Jian Huang
Katherine E Berquam-Vrieze
P2860
P304
P356
10.1371/JOURNAL.PONE.0024668
P407
P577
2011-09-13T00:00:00Z