The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids
about
Molecular targets for flavivirus drug discoveryStructure and functionality in flavivirus NS-proteins: perspectives for drug designFunctional cross-talk between distant domains of chikungunya virus non-structural protein 2 is decisive for its RNA-modulating activityFlaviviral Replication Complex: Coordination between RNA Synthesis and 5'-RNA CappingJapanese encephalitis: the virus and vaccinesSynergistic interactions between the NS3(hel) and E proteins contribute to the virulence of dengue virus type 1ATP binding and ATPase activities associated with recombinant rabbit hemorrhagic disease virus 2C-like polypeptide.cis- and trans-acting elements in flavivirus RNA replicationtrans-Complementation analysis of the flavivirus Kunjin ns5 gene reveals an essential role for translation of its N-terminal half in RNA replicationEfficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicasePurification and Characterization of West Nile Virus Nucleoside Triphosphatase (NTPase)/Helicase: Evidence for Dissociation of the NTPase and Helicase Activities of the EnzymeMutagenesis of the Dengue virus type 2 NS3 protein within and outside helicase motifs: effects on enzyme activity and virus replication.Structure of the Flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing.Structure of the Dengue Virus Helicase/Nucleoside Triphosphatase Catalytic Domain at a Resolution of 2.4 ADengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion.Derivation and characterization of a dengue type 1 host range-restricted mutant virus that is attenuated and highly immunogenic in monkeys.Complementation analysis of the flavivirus Kunjin NS3 and NS5 proteins defines the minimal regions essential for formation of a replication complex and shows a requirement of NS3 in cis for virus assembly.Langat Flavivirus Protease NS3 Binds Caspase-8 and Induces ApoptosisProbing the substrate specificity of the dengue virus type 2 NS3 serine protease by using internally quenched fluorescent peptidesStructure-Based Mutational Analysis of the NS3 Helicase from Dengue VirusWest Nile Virus 5'-Cap Structure Is Formed by Sequential Guanine N-7 and Ribose 2'-O Methylations by Nonstructural Protein 5Molecular and Functional Analyses of Kunjin Virus Infectious cDNA Clones Demonstrate the Essential Roles for NS2A in Virus Assembly and for a Nonconservative Residue in NS3 in RNA ReplicationRecent Advances in Deciphering Viral and Host Determinants of Dengue Virus Replication and PathogenesisDe Novo Synthesis of Negative-Strand RNA by Dengue Virus RNA-Dependent RNA Polymerase In Vitro: Nucleotide, Primer, and Template ParametersStructure and Function of Flavivirus NS5 MethyltransferaseDistinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation EventsThe Two-component NS2B-NS3 Proteinase Represses DNA Unwinding Activity of the West Nile Virus NS3 HelicaseGenetic Interactions among the West Nile Virus Methyltransferase, the RNA-Dependent RNA Polymerase, and the 5' Stem-Loop of Genomic RNAIdentification and Biochemical Characterization of Small-Molecule Inhibitors of West Nile Virus Serine Protease by a High-Throughput ScreenInsights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 proteinMechanism of NS2B-Mediated Activation of NS3pro in Dengue Virus: Molecular Dynamics Simulations and BioassaysPotential High-Throughput Assay for Screening Inhibitors of West Nile Virus ReplicationConservation and Variability of West Nile Virus ProteinsCyclosporine Inhibits Flavivirus Replication through Blocking the Interaction between Host Cyclophilins and Viral NS5 ProteinCrystal Structure of a Novel Conformational State of the Flavivirus NS3 Protein: Implications for Polyprotein Processing and Viral ReplicationEffects of detergents on the West Nile virus protease activityNSs Encoded by Groundnut Bud Necrosis Virus Is a Bifunctional EnzymeHigh affinity human antibody fragments to dengue virus non-structural protein 32'-O methylation of internal adenosine by flavivirus NS5 methyltransferaseNovel cis-acting element within the capsid-coding region enhances flavivirus viral-RNA replication by regulating genome cyclization
P2860
Q21999123-E4F1732D-DDF5-47CA-BA49-BB4E3A16FFBCQ23011530-A5E470DE-9472-43DE-AD20-FB268B7B12DBQ24701782-2A0A7B39-2B8E-45DC-B5F1-C316A3FBB114Q26796618-835EF25A-8F66-49AA-882A-25A40264FBCCQ27010434-77E5C34F-8C4D-4B59-A95E-01BA06322388Q27305534-19CE8001-4277-491D-A685-5CC47EE49D71Q27469603-5ADF4988-7703-458F-B865-6325F6C7BCD4Q27469649-E1B198D0-CA1C-4079-9859-5B657421CB9CQ27469741-A4692768-8EB6-4A05-902C-D906B42282CEQ27469756-73013CD0-0E92-4C14-AD4C-969470D68AFCQ27469780-E6879322-E23A-49EE-9B74-88CE11E8A9EEQ27469868-EDC16E4D-329D-4F69-8CD4-56F0CFF6CB99Q27470433-19CA0138-C0C5-4D7E-A88E-04F8EAEE054CQ27470453-8B671BAC-026D-4FA1-A544-596A6BF13CA4Q27470758-A56F6CB6-5169-4EBC-B39C-06E6E759A0D8Q27472847-77CE8B5B-8FA7-4169-A4D0-273B0B5DAE0AQ27472910-01D94C08-5579-4A5A-8A36-08B04CC28744Q27472960-D5EA8739-312D-4DEF-9536-0AE74DBD9537Q27473256-EA8FF59D-773D-43C4-8258-01645CEB9E05Q27473280-B5832FA6-02CE-48E7-9EAF-B8316B4615FCQ27477465-89550F42-FA97-4EED-8BDB-995631B3647DQ27477562-B67C21B3-1832-4E9C-8445-CCBA1EE6AF93Q27477646-2C30102F-BF9B-440D-9ABE-BA339035D8EFQ27477711-457C25AA-A38B-4CC2-BBA4-815C5472FA5EQ27478377-1C301673-809C-4DE6-BE9F-86A3E19193A2Q27480347-CFCF64AF-1946-4350-87AE-C8D160011D14Q27486257-B347D972-CA7E-441B-A963-864FA4F9BA78Q27486408-31467E44-A677-48D2-94A8-8A98E02FC3F8Q27486814-3A9AE5F6-8E40-4BC2-A0AA-8D21292890CCQ27487462-7FD3F4E4-AA65-447D-A4EE-190CD80C2E9EQ27487532-ABDB86C8-1522-42C5-B176-8A2958A890DBQ27487569-BE64397B-2A93-4EA3-9E5A-22882EA29659Q27488320-CEDE2387-48AC-4A87-B14C-FAFD20208DFDQ27488982-9BE3B49C-ED08-4167-AA67-84E3B9A498F5Q27490476-A18A92D6-F3F2-4FF4-8403-D13F141859FAQ27490897-C3C3A4B0-217F-4C6C-BECA-68CD28C24C73Q27491297-E5A2D87F-9507-4AE7-A26D-E05ACAB62520Q28476043-83B9F1C2-60A0-4357-905F-881ADF4B9AF8Q28482139-80AA4A20-81A3-46FB-A973-6C20CC3DFE32Q28681742-B4555914-C71B-42A5-B0E9-BD82F39D5654
P2860
The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The serine protease and RNA-st ...... hin a region of 20 amino acids
@ast
The serine protease and RNA-st ...... hin a region of 20 amino acids
@en
The serine protease and RNA-st ...... hin a region of 20 amino acids
@nl
type
label
The serine protease and RNA-st ...... hin a region of 20 amino acids
@ast
The serine protease and RNA-st ...... hin a region of 20 amino acids
@en
The serine protease and RNA-st ...... hin a region of 20 amino acids
@nl
prefLabel
The serine protease and RNA-st ...... hin a region of 20 amino acids
@ast
The serine protease and RNA-st ...... hin a region of 20 amino acids
@en
The serine protease and RNA-st ...... hin a region of 20 amino acids
@nl
P2093
P2860
P1433
P1476
The serine protease and RNA-st ...... hin a region of 20 amino acids
@en
P2093
P2860
P304
P577
1999-04-01T00:00:00Z