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Structure and Function of Flavivirus NS5 Methyltransferase

Structure and Function of Flavivirus NS5 Methyltransferase

http://www.wikidata.org/entity/Q27478377

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Analysis of RNA binding by the dengue virus NS5 RNA capping enzyme Molecular targets for flavivirus drug discovery Identification of a novel antiviral inhibitor of the flavivirus guanylyltransferase enzyme Structure and functionality in flavivirus NS-proteins: perspectives for drug design Inhibition of protein kinase C promotes dengue virus replication Structural and Functional Analyses of a Conserved Hydrophobic Pocket of Flavivirus Methyltransferase Enzymology of RNA cap synthesis Maturation of dengue virus nonstructural protein 4B in monocytes enhances production of dengue hemorrhagic fever-associated chemokines and cytokines Innate immunity evasion by Dengue virus Structural proteomics of dengue virus In vitro resistance selection and in vivo efficacy of morpholino oligomers against West Nile virus Functions of the 3' and 5' genome RNA regions of members of the genus Flavivirus Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase Using the Hepatitis C Virus RNA-Dependent RNA Polymerase as a Model to Understand Viral Polymerase Structure, Function and Dynamics The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing Viral RNA switch mediates the dynamic control of flavivirus replicase recruitment by genome cyclization Illustrating and homology modeling the proteins of the Zika virus.A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication Distinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation Events Interaction between the Cellular Protein eEF1A and the 3'-Terminal Stem-Loop of West Nile Virus Genomic RNA Facilitates Viral Minus-Strand RNA Synthesis Vesicular Stomatitis Virus mRNA Capping Machinery Requires Specific cis-Acting Signals in the RNA Structural insights into the mechanism and evolution of the vaccinia virus mRNA cap N7 methyl-transferase West Nile Virus Methyltransferase Catalyzes Two Methylations of the Viral RNA Cap through a Substrate-Repositioning Mechanism Genetic Interactions among the West Nile Virus Methyltransferase, the RNA-Dependent RNA Polymerase, and the 5' Stem-Loop of Genomic RNA Separate molecules of West Nile virus methyltransferase can independently catalyze the N7 and 2′-O methylations of viral RNA cap Phosphorylation of yellow fever virus NS5 alters methyltransferase activity Analysis of a structural homology model of the 2'-O-ribose methyltransferase domain within the vesicular stomatitis virus L protein.Identification of Sendai Virus L Protein Amino Acid Residues Affecting Viral mRNA Cap Methylation Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase Analysis of Flavivirus NS5 Methyltransferase Cap Binding Cyclosporine Inhibits Flavivirus Replication through Blocking the Interaction between Host Cyclophilins and Viral NS5 Protein Exclusion of West Nile Virus Superinfection through RNA Replication The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure Focus on flaviviruses: current and future drug targets Crystal Structure of the Dengue Virus Methyltransferase Bound to a 5′-Capped Octameric RNA Small Molecule Inhibitors That Selectively Block Dengue Virus Methyltransferase Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex Membrane Topology and Function of Dengue Virus NS2A Protein Crystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interface RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state

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Structure and Function of Flavivirus NS5 Methyltransferase

http://www.wikidata.org/entity/Q27478377

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2007 nî lūn-bûn

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2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2007 թվականի ապրիլին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Structure and Function of Flavivirus NS5 Methyltransferase

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Structure and Function of Flavivirus NS5 Methyltransferase

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Structure and Function of Flavivirus NS5 Methyltransferase

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type

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Structure and Function of Flavivirus NS5 Methyltransferase

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Structure and Function of Flavivirus NS5 Methyltransferase

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Structure and Function of Flavivirus NS5 Methyltransferase

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Structure and Function of Flavivirus NS5 Methyltransferase

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Structure and Function of Flavivirus NS5 Methyltransferase

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Structure and Function of Flavivirus NS5 Methyltransferase

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Journal of Virology

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Structure and Function of Flavivirus NS5 Methyltransferase

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P2093

Debashish Ray

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Hongping Dong

http://www.w3.org/2001/XMLSchema#string

Suping Ren

http://www.w3.org/2001/XMLSchema#string

Yangsheng Zhou

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Yi Guo

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Yiwei Zhao

http://www.w3.org/2001/XMLSchema#string

Zhong Li

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P2860

A 5' RNA element promotes dengue virus RNA synthesis on a circular genome

Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase

Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II

High-throughput detection of West Nile virus RNA

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids

An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization

High-throughput assays using a luciferase-expressing replicon, virus-like particles, and full-length virus for West Nile virus drug discovery.

Infectious cDNA clone of the epidemic west nile virus from New York City

Triaryl pyrazoline compound inhibits flavivirus RNA replication.

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3891-903

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scholarly article

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3225608

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P356

10.1128/JVI.02704-06

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8

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81

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Kristen A Bernard

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2007-04-01T00:00:00Z

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17267492

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1866096

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