Antisense oligonucleotide induced exon skipping and the dystrophin gene transcript: cocktails and chemistries
about
Progress toward therapy with antisense-mediated splicing modulationNanopolymers improve delivery of exon skipping oligonucleotides and concomitant dystrophin expression in skeletal muscle of mdx mice.Proteomic profiling of antisense-induced exon skipping reveals reversal of pathobiochemical abnormalities in dystrophic mdx diaphragm.Rational design of antisense oligomers to induce dystrophin exon skipping.Dystrophin isoform induction in vivo by antisense-mediated alternative splicing.Mismatched single stranded antisense oligonucleotides can induce efficient dystrophin splice switching.Optimizing exon skipping therapies for DMD.In-frame dystrophin following exon 51-skipping improves muscle pathology and function in the exon 52-deficient mdx mouse.Personalized exon skipping strategies to address clustered non-deletion dystrophin mutations.Improved antisense oligonucleotide design to suppress aberrant SMN2 gene transcript processing: towards a treatment for spinal muscular atrophyMultiple exon skipping strategies to by-pass dystrophin mutations.Targeted exon skipping to address "leaky" mutations in the dystrophin gene.Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections.Novel compounds for the treatment of Duchenne muscular dystrophy: emerging therapeutic agentsAntisense suppression of donor splice site mutations in the dystrophin gene transcript.Targeted exon skipping to correct exon duplications in the dystrophin gene.Potential therapeutic applications of antisense morpholino oligonucleotides in modulation of splicing in primary immunodeficiency diseasesDesign of phosphorodiamidate morpholino oligomers (PMOs) for the induction of exon skipping of the human DMD gene.Detection of Helicobacter pylori in the Gastric Mucosa by Fluorescence In Vivo Hybridization.Prediction of antisense oligonucleotides using structural and thermodynamic motifs.Ameliorating pathogenesis by removing an exon containing a missense mutation: a potential exon-skipping therapy for laminopathies.Application of locked nucleic acid-based probes in fluorescence in situ hybridization.Antisense Oligonucleotide-Mediated Terminal Intron Retention of the SMN2 Transcript.Construction of a tri-chromatic reporter cell line for the rapid and simple screening of splice-switching oligonucleotides targeting DMD exon 51 using high content screening.
P2860
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P2860
Antisense oligonucleotide induced exon skipping and the dystrophin gene transcript: cocktails and chemistries
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
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2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Antisense oligonucleotide indu ...... ipt: cocktails and chemistries
@ast
Antisense oligonucleotide indu ...... ipt: cocktails and chemistries
@en
Antisense oligonucleotide indu ...... ipt: cocktails and chemistries
@nl
type
label
Antisense oligonucleotide indu ...... ipt: cocktails and chemistries
@ast
Antisense oligonucleotide indu ...... ipt: cocktails and chemistries
@en
Antisense oligonucleotide indu ...... ipt: cocktails and chemistries
@nl
prefLabel
Antisense oligonucleotide indu ...... ipt: cocktails and chemistries
@ast
Antisense oligonucleotide indu ...... ipt: cocktails and chemistries
@en
Antisense oligonucleotide indu ...... ipt: cocktails and chemistries
@nl
P2093
P2860
P356
P1476
Antisense oligonucleotide indu ...... ipt: cocktails and chemistries
@en
P2093
Abbie M Adams
Catherine Coleman
Penny L Harding
Steve D Wilton
P2860
P2888
P356
10.1186/1471-2199-8-57
P577
2007-07-02T00:00:00Z