The three-dimensional structure of Asp189Ser trypsin provides evidence for an inherent structural plasticity of the protease
about
N-terminal protein modification by substrate-activated reverse proteolysisA serpin-induced extensive proteolytic susceptibility of urokinase-type plasminogen activator implicates distortion of the proteinase substrate-binding pocket and oxyanion hole in the serpin inhibitory mechanism.Disulfide locked variants of factor VIIa with a restricted beta-strand conformation have enhanced enzymatic activitySpecificity of trypsin and chymotrypsin: loop-motion-controlled dynamic correlation as a determinant.Mechanisms and specificity of factor XIa and trypsin inhibition by protease nexin 2 and basic pancreatic trypsin inhibitorResidues crucial for maintaining short paths in network communication mediate signaling in proteinsModular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages.Protein conformational plasticity and complex ligand-binding kinetics explored by atomistic simulations and Markov models.Residue Asp-189 controls both substrate binding and the monovalent cation specificity of thrombin.
P2860
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P2860
The three-dimensional structure of Asp189Ser trypsin provides evidence for an inherent structural plasticity of the protease
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The three-dimensional structur ...... ral plasticity of the protease
@ast
The three-dimensional structur ...... ral plasticity of the protease
@en
The three-dimensional structur ...... ral plasticity of the protease
@nl
type
label
The three-dimensional structur ...... ral plasticity of the protease
@ast
The three-dimensional structur ...... ral plasticity of the protease
@en
The three-dimensional structur ...... ral plasticity of the protease
@nl
prefLabel
The three-dimensional structur ...... ral plasticity of the protease
@ast
The three-dimensional structur ...... ral plasticity of the protease
@en
The three-dimensional structur ...... ral plasticity of the protease
@nl
P2093
P2860
P1433
P1476
The three-dimensional structur ...... ral plasticity of the protease
@en
P2093
P2860
P356
10.1046/J.1432-1327.1999.00452.X
P407
P577
1999-07-01T00:00:00Z