Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages.
about
Coarse-grained description of protein internal dynamics: an optimal strategy for decomposing proteins in rigid subunitsStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewDesign principles underpinning the regulatory diversity of protein kinasesPerturbation-based Markovian transmission model for probing allosteric dynamics of large macromolecular assembling: a study of GroEL-GroESSignal Transduction Pathways in the Pentameric Ligand-Gated Ion ChannelsMoonlighting characteristics of G protein-coupled receptors: focus on receptor heteromers and relevance for neurodegeneration.Reconstruction and Application of Protein-Protein Interaction NetworkThe modular organization of domain structures: insights into protein-protein bindingMaximum entropy reconstructions of dynamic signaling networks from quantitative proteomics dataAllosteric signalling in the outer membrane translocation domain of PapC usher.Thermostability of in vitro evolved Bacillus subtilis lipase A: a network and dynamics perspective.Functional correlation of bacterial LuxS with their quaternary associations: interface analysis of the structure networks.Characteristics Analyses and Comparisons of the Protein Structure Networks Constructed by Different Methods.Integration of evolutionary features for the identification of functionally important residues in major facilitator superfamily transportersRING: networking interacting residues, evolutionary information and energetics in protein structures.Allosteric communication in cysteinyl tRNA synthetase: a network of direct and indirect readout.Mapping the mutual information network of enzymatic families in the protein structure to unveil functional features.Protein structure networks.Computational modeling of allosteric communication reveals organizing principles of mutation-induced signaling in ABL and EGFR kinases.The energy landscape analysis of cancer mutations in protein kinasesImplications from a network-based topological analysis of ubiquitin unfolding simulations.Prediction by graph theoretic measures of structural effects in proteins arising from non-synonymous single nucleotide polymorphisms.A combinatorial approach to detect coevolved amino acid networks in protein families of variable divergence.Structure-based predictive models for allosteric hot spots.Protein fragments: functional and structural roles of their coevolution networks.Induced fit, conformational selection and independent dynamic segments: an extended view of binding eventsDefining structural and evolutionary modules in proteins: a community detection approach to explore sub-domain architecture.Molecular-docking study of malaria drug target enzyme transketolase in Plasmodium falciparum 3D7 portends the novel approach to its treatment.Computational Analysis of Residue Interaction Networks and Coevolutionary Relationships in the Hsp70 Chaperones: A Community-Hopping Model of Allosteric Regulation and CommunicationMigration of small ligands in globins: Xe diffusion in truncated hemoglobin N.Coevolution analysis of Hepatitis C virus genome to identify the structural and functional dependency network of viral proteins.Amino acid substitutions in the sugar kinase/hsp70/actin superfamily conserved ATPase core of E. coli glycerol kinase modulate allosteric ligand affinity but do not alter allosteric coupling.Local packing modulates diversity of iron pathways and cooperative behavior in eukaryotic and prokaryotic ferritins.On the expanding terminology in the GPCR field: the meaning of receptor mosaics and receptor heteromers.HotRegion: a database of predicted hot spot clustersBIS2Analyzer: a server for co-evolution analysis of conserved protein families.Prediction of allosteric sites and mediating interactions through bond-to-bond propensities.Site selectivity for protein tyrosine nitration: insights from features of structure and topological network.Distinct allostery induced in the cyclic GMP-binding, cyclic GMP-specific phosphodiesterase (PDE5) by cyclic GMP, sildenafil, and metal ionsPossible new targets for GPCR modulation: allosteric interactions, plasma membrane domains, intercellular transfer and epigenetic mechanisms.
P2860
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P2860
Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Modular architecture of protei ...... teins and regulatory linkages.
@ast
Modular architecture of protei ...... teins and regulatory linkages.
@en
type
label
Modular architecture of protei ...... teins and regulatory linkages.
@ast
Modular architecture of protei ...... teins and regulatory linkages.
@en
prefLabel
Modular architecture of protei ...... teins and regulatory linkages.
@ast
Modular architecture of protei ...... teins and regulatory linkages.
@en
P2860
P50
P356
P1433
P1476
Modular architecture of protei ...... teins and regulatory linkages.
@en
P2093
Dolors Amoros
P2860
P2888
P356
10.1186/GB-2007-8-5-R92
P577
2007-01-01T00:00:00Z
P5875
P6179
1042929417