Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase
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Retroviral intasome assembly and inhibition of DNA strand transferMultifunctional facets of retrovirus integraseCrystal structure of the Rous sarcoma virus intasome.Structural basis for functional tetramerization of lentiviral integraseCrystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA bindingStructure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein.Functional and structural characterization of the integrase from the prototype foamy virusCrystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding siteCrystal structures of catalytic core domain of BIV integrase: implications for the interaction between integrase and target DNAA Crystal Structure of the Catalytic Core Domain of an Avian Sarcoma and Leukemia Virus Integrase Suggests an Alternate Dimeric AssemblyA possible role for the asymmetric C-terminal domain dimer of Rous sarcoma virus integrase in viral DNA bindingRetroviral Integrase: Then and NowHIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cellsHuman immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes.Localization of ASV integrase-DNA contacts by site-directed crosslinking and their structural analysisStructural and sequencing analysis of local target DNA recognition by MLV integrase.Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase.Soluble expression, purification and characterization of the full length IS2 Transposase.Structural basis for HIV-1 DNA integration in the human genome, role of the LEDGF/P75 cofactorArchitecture of a full-length retroviral integrase monomer and dimer, revealed by small angle X-ray scattering and chemical cross-linkingAn inhibitory monoclonal antibody binds at the turn of the helix-turn-helix motif in the N-terminal domain of HIV-1 integrase.Structural and functional role of INI1 and LEDGF in the HIV-1 preintegration complex.Targeting Tn5 transposase identifies human immunodeficiency virus type 1 inhibitors.Nucleophile selection for the endonuclease activities of human, ovine, and avian retroviral integrases.Revealing domain structure through linker-scanning analysis of the murine leukemia virus (MuLV) RNase H and MuLV and human immunodeficiency virus type 1 integrase proteinsRous sarcoma virus synaptic complex capable of concerted integration is kinetically trapped by human immunodeficiency virus integrase strand transfer inhibitors.Structural properties of HIV integrase. Lens epithelium-derived growth factor oligomers.Pathogenicity and rapid growth kinetics of feline immunodeficiency virus are linked to 3' elements.Structure-based modeling of the functional HIV-1 intasome and its inhibitionStructural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75.Molecular dynamics studies of the wild-type and double mutant HIV-1 integrase complexed with the 5CITEP inhibitor: mechanism for inhibition and drug resistanceComparison of multiple molecular dynamics trajectories calculated for the drug-resistant HIV-1 integrase T66I/M154I catalytic domain.Division of labor within human immunodeficiency virus integrase complexes: determinants of catalysis and target DNA captureHIV integrase, a brief overview from chemistry to therapeutics.Metal binding by the D,DX35E motif of human immunodeficiency virus type 1 integrase: selective rescue of Cys substitutions by Mn2+ in vitroRetroviral DNA integration: reaction pathway and critical intermediates.Retroviral Integrase Structure and DNA Recombination MechanismHIV-1 integrase and RNase H activities as therapeutic targets.Molecular and genetic determinants of rous sarcoma virus integrase for concerted DNA integration.Targeting HIV-1 integrase.
P2860
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P2860
Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase
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2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2000 թվականի փետրվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase
@ast
Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase
@en
Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase
@nl
type
label
Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase
@ast
Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase
@en
Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase
@nl
prefLabel
Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase
@ast
Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase
@en
Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase
@nl
P2093
P356
P1476
Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase
@en
P2093
P304
P356
10.1006/JMBI.1999.3463
P407
P577
2000-02-18T00:00:00Z