An inhibitory monoclonal antibody binds at the turn of the helix-turn-helix motif in the N-terminal domain of HIV-1 integrase.
about
Architecture of a full-length retroviral integrase monomer and dimer, revealed by small angle X-ray scattering and chemical cross-linkingMapping the epitope of an inhibitory monoclonal antibody to the C-terminal DNA-binding domain of HIV-1 integrase.Mode of inhibition of HIV-1 Integrase by a C-terminal domain-specific monoclonal antibody.Revealing domain structure through linker-scanning analysis of the murine leukemia virus (MuLV) RNase H and MuLV and human immunodeficiency virus type 1 integrase proteinsThe HIV-1 integrase α4-helix involved in LTR-DNA recognition is also a highly antigenic peptide elementHIV-1 IN inhibitors: 2010 update and perspectivesMechanisms and inhibition of HIV integrationRecombinant rabbit single-chain antibodies bind to the catalytic and C-terminal domains of HIV-1 integrase protein and strongly inhibit HIV-1 replicationIn search of authentic inhibitors of HIV-1 integration.Targeting HIV-1 integrase.Why specific anti-integrase antibodies from HIV-infected patients can efficiently hydrolyze 21-mer oligopeptide corresponding to antigenic determinant of human myelin basic protein.Computer applications for prediction of protein-protein interactions and rational drug design.Anti-integrase abzymes from the sera of HIV-infected patients specifically hydrolyze integrase but nonspecifically cleave short oligopeptides.
P2860
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P2860
An inhibitory monoclonal antibody binds at the turn of the helix-turn-helix motif in the N-terminal domain of HIV-1 integrase.
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
An inhibitory monoclonal antib ...... nal domain of HIV-1 integrase.
@ast
An inhibitory monoclonal antib ...... nal domain of HIV-1 integrase.
@en
type
label
An inhibitory monoclonal antib ...... nal domain of HIV-1 integrase.
@ast
An inhibitory monoclonal antib ...... nal domain of HIV-1 integrase.
@en
prefLabel
An inhibitory monoclonal antib ...... nal domain of HIV-1 integrase.
@ast
An inhibitory monoclonal antib ...... nal domain of HIV-1 integrase.
@en
P2093
P2860
P356
P1476
An inhibitory monoclonal antib ...... nal domain of HIV-1 integrase.
@en
P2093
P2860
P304
38739-38748
P356
10.1074/JBC.M005499200
P407
P577
2000-12-01T00:00:00Z